Special

MmuINT0104090 @ mm9

Intron Retention

Gene
ENSMUSG00000020527 | Myo19
Description
myosin XIX [Source:MGI Symbol;Acc:MGI:1913446]
Coordinates
chr11:84714344-84715005:+
Coord C1 exon
chr11:84714344-84714520
Coord A exon
chr11:84714521-84714852
Coord C2 exon
chr11:84714853-84715005
Length
332 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
3' ss Seq
GCCCTTGCCCTTTCCGATAGGAC
3' ss Score
9.94
Exon sequences
Seq C1 exon
GAATGCCGCCTTAACCGGCCAAGCAGTGCAGCACAACTACAGACGCGCATCGAGAGCACGCTGGCAGGACGGCCCTGCCTGGGCCATAACAAGCTCAGCCGGGAGCCCAGCTTCGTGGTTGTGCATTTCGCGGGACCTGTACGGTACCACACAGCCGGCCTGGTGGAAAAGAACAAG
Seq A exon
GTAAGCCTGGGCCACAGCATAGAGCTACCGGATAAGGAAGCTGAGTCACTACTGCATATACAAAGTAGTTCCTGTAGGGCATCTACTTTCTCCTCAGTGTCCTTTCCTCAAAATCCAATCTCACTCTCTTGAGCCCTGCCTAGGATCTTTGCTAATCCATCCTGAGCTGCCTGGAAGTGGTCCATGTACACATGGCTCCTCTTGGCCCGCAGACCCAGTCTTCTTGGGATTCCAGCCTGCCCTCCCCAGGAGCCCTGGTCATGGGGGGAGGGGGTGGCCAGCACTAGGAAGCAGCTCACCTCTCTGTCTGCCGCCCTTGCCCTTTCCGATAG
Seq C2 exon
GACCCTGTTCCCCCTGAGCTGACTGAGCTCCTGCAGCAATCCCAAGACCCCCTGCTCACGATGCTGTTTCCTGCCAACCCTGAAGAGAAGACCCAGGAGGAGCTGTCTGGCCAGAGCCGGGCTCCTGCATTGACTGTGGTGTCCAAGTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020527-Myo19:NM_025414:16
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.119 A=NA C2=0.569
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=FE(8.9=100)

							
A:
NA

							
C2:
PF0006316=Myosin_head=FE(7.7=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000091502f6139A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000091502, ENSMUSP00000091502f764A
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr17:34862448-34862801 
HsaINT0108441
(MYO19)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr19:13167162-13167472 
LOW PSI
BtaINT0097862
(MYO19)
Chicken
(galGal4)
chr19:8133068-8133356 
ALTERNATIVE
GgaINT0130573
(MYO19)
Chicken
(galGal3)
chr19:8086694-8086982 
ALTERNATIVE
GgaINT0130573
(MYO19)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCTTAACCGGCCAAGCAGTG

				
R: 
TGAACTTGGACACCACAGTCA

				
Band lengths: 
320-652

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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