MmuINT0166432 @ mm9
Intron Retention
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28521076-28526564:+
Coord C1 exon
chr2:28521076-28521149
Coord A exon
chr2:28521150-28526388
Coord C2 exon
chr2:28526389-28526564
Length
5239 bp
Sequences
Splice sites
5' ss Seq
AAGGTACAA
5' ss Score
6.82
3' ss Seq
ACTTGTGTTGCCTTTTCTAGGTG
3' ss Score
12.51
Exon sequences
Seq C1 exon
CCAATGATGGAGCATGTGCGAATTCACCCGGAATTAGTGACTGGATCCAAGGACCATGAACTGGACCCTCGAAG
Seq A exon
GTACAAAAACTAAATTAGTGACAGAATCTTTGAGTCTCTTAAGAGATTGAAAATGTGATCTACAGATACCTGTGGGGATACAGATATTCCACTGGTACAATGGGCTGGAACTTGAAATCTAAAACACTCCTCAGAGAGAGCTACTGACTCTGTGAGCAGAGCAGAGGCGGTGGCAGCTACTGCCTGTGCCTGGAAGCCCAGGAAGGTTGCTTTTTGTATTTGAGTGGGTTGGGAGGTTAATTGGGAAGCCAAAAACTAGGAGATTACAGAGAGTCCAGATCTGGAGTTATGAGCCTCCATGGGTCCCTTTCTCCATAAGCATTGCCAGGTGTCTGATTTCTCCCTTCCCAACCACCATGGGCCCTGCAGGAATTTCCAGGTGTTTCCTGAGGAGCTACTGGACCTGCTGAGTTGCAAGAAGCACGGCTCCTTCTGCCTGTCAGGCAGATTTACGATTCCCAGTGAGGGGATGGAAGCTTTGGGGCAGGGAGGCGTAGGGGGGAACTGAGCTAGGAGGTGTCAAGTCTCTGCAATTTTAAAAAGACTGACTTATGCCTGATAATCCTTATAAAGTTGTACCTCTACAGTCTACTTCTGTGGTGCAGCCTCAGTCAGCTTAAAGTAAGCTGTAATAGCATACAAACATGTTAGTTCTGTCTTAGAAGCTGTTCCTCTCTGCTCCCTGTCCACCCTGAGGTGGACAAGCAGCTGCTGCCTTGCCTTTATTCTCACTGTTCTTTCTGTAGTTTGCCGTATGTTTTGAGAGCTGATTGCTGTTAGATGAGGATAGAAGCATTGTCAGCCTTGGACCTGGCTTCATCTTCTTTAAGTGTGCCTCAGGGAAGTCATTGTAAGAGGTCACAAGTGCGGCATGGGGAGCACAGGCTATTTCTTCTAAGCTCCTCATTTACTTGTTTTGATTTGTCCGTTTTAAGTCATTGAGGCTTCTCATAAAGCTTTGGTGATTCTCTCGTGCTTGGGTGGGAAGACAGGAACTCTGCTGGTGAGGTTGGGGGTTGGTGTCTTGATCTAGAGCATTTCTGTGTGGATCTGAGCATCTAGGGGTCGATACCAACACTGGGATTGTGTTGTGAGCTTTCAGACTCCTAAAGGTTGTTCAGTATATGGGAGCTGACTGGTAGCTCGAAGCTTTGGCTTAGGACGTTGCTTTTGTGGTTGGACATCCCTGTCTGCTGCTCTCCAGACTTAGATACTATGCTCTCTGTCTTCTTTTTCTCCCTATGCTTTGTATTTGAAAATAGGTCTTTATTATAGATGGTGGGACGTCAGGAGATTGTACAGTGGGGTGAAGGTGTTCAGTCAGCCATATTAGCTGGGGACCTTCCCTCTCAGTATTGCACATAGCACCTCAGTGCCTGGCTCTGTCTGCTGTGATGAGGCAAGGGAGCCAGGAAGGAAACATTGAGAGCAAAGCCATAGAGCAGCCAATTGTGCATGGTTATGGGGCCAGGGTGACACAGTAAGAGGCACTCTGATATAGTAGAAATCTCTTGAAATGAAAATGAACTCCCAAATAAGTATTTCAGCTAAGGAGCTGGAGTAGAGCCGAGACTGGCTCAGCTGAACAGAGGGCAGAGGCAGGTGACAGAGCAGATTTGGAAGGTTGGGTGGAGTCCAATAGCCAAGGAAAACACGTGTAAAAGGAGAAGAGGACGCTTCCATGGGAGAATTTGTAAAAGAAATGTCCTGTAGTTGAAGCTTCTGGATTGAAGGTCAAGTGCACAGCTCCATCAGTGCGAAGGAATGCTGCCCAGCCTCAGCTTTGTGAGATTTCAGAACATCAGAAGAATAAACCTTTCAGAGAGTGCAAAGATAAAAATACTCAGACACTTAACCGGAACCGGAAGTCAGGGTAGTGTTAGCTTCTCAACCCTTCAAGGAGGTTCCGGGTAAGAGTTCTGTGCTGTGGAGCTCTTTTAGACAGGCCAAGACTCGGAGTTTTCAGTTACCCCATTGCACCCCCAGCTGGCTATGGGAGGGTGTTCTACCAAATGAGCCCAAGAAGGGTGGGGCTGGGTGTAGGCTGGTCAAAGAGGTGTCAGAACAGTGAGCCAGAGACTGACGCAGCTCCAGAAGGGAGCCCACTGAGGAGAGGGGACTAACTCTGGTAGATTGTGCATCTCATTATATGAGAGGAGCAGTGGGCATCAGTCTAGAGTGACAGGGTAGTTCAGTCAGCATTGGACACATCACAGACTGGGAGAAGGGAGCAATGCCAGGTCACACCACATGAGAAACTGTATCAGAGCCCTCCAGCCTGCTGGGATTGGTGCTTACGTAGTCTTAATAATTGTTTAACTAAATTTTGGAAGAAAAGAGAAAAAGAAAAGAGTTAACTTGAGGAGGAGGGAAAGAATGCATGGCAGTGATCCTGGTCCTCAGAGCAAGTTAATAAACGAGAAGCATAGAGTGCATTTGCTGAGCCTTGAGGAGTCGGGGAAGCAGTTCAGCTAGCAGAGCTGGAGGCAGTAGCCAGGGTAGTCACAGAGAACAGTGTGGGTACCTGTAGCATGGCACTGACTTGTTTCTGGTTTTTGAGACAAGGTCTCCCCATATAGTCCAGGTGGCACAGTCTCGTGTCTCCATCCTCCCTGGCACTGGGATCATAGGCTGTGGGGACTATAAGCTGCCATACTTCAGTGACTCTGAGATGCCATCAAATGCACAACACACATTTTATGTGAATCTGAGACGGATACCAGCTAAACAAATGTGTAGCTGATAAGATTGCAGTTTGCAATTTTAGAGACATTAAAATATAGACAGTCTATTTAAACCAGGGATGGTGGCCCACATTAACTTCTAGTACTAGGGTGGCAGAGGCAGGTGAATTTCTGAGTTTGAGGCCAGCCTGGTCTACAGAGTGAGTTCTAGGACAATTAGGGCTGCACAGAGAAACCCTGTCTCAAGAAAACTAAATACAAAATTTTTAAATAAATTTATTTAAGTATCATGGAAATACAGTGAATGCTTTTCTTGATCTTTAAATAAAACATTTAGAGCAAGTGAGATGGGCCAGTGGCTGAAGGCATCAGCTGCCAAGCTGAGGACCTGAAGCCACATGGTGGAAGGAGAGAGCCAACCCCCACAAGTTGTCCTCTGACCTCTTCAGGTGCACGCTATTACACACAAAAGAATTGTCAAAATATTTAACGGGGTGCTTTTCTAGCATGTGTTTAATCCTGAGCACTACAAACATAAGTAAAACATCTAATATTATTCTCTTTTATTTTTATTTACTTATTTCTCTGTCTGTGTGCATGCATGAGCCATGTGTCCGTGGAGGTCAGAGGACACCTTATTGGGATCATTTTCTGTTTCTGTCGTGTAGGTGGGTTCCTAGGCCTAAACCTGGGCAGTCAGGATTGGCGGCAGATGTCTACCTGAAAAGTCCTCTTGCCATTCATTTGGCTCTTTTTCTTTTTATAAGAAATCTTATTTCCTTTACTAAAATTAATCTTGTGTGTATATGTGTCCTGACTTGCTCCTTGCTAAATCACGGTGTAGTGATGCTGAGGGTGTGGAAAGAGGAGCCTTCCCCACTGTACCACCATACACGTAGGTACAGCTCTGTGCTCTACAAGCAACTTTGTGCTTGGTCAGTGCGCACAGTCTAAGTGTCCTTTTGGTTTGGGGCATCTGCAGAACATCTGGCAGACTCAGAAGAGATAAAAAAAGAAAGCAAGAGAATTAATGTTGCCTGTAATGCCAGGTTTTTATAGTGCTGGAGATTAAACAGAGGCCTTGCAGATGTTGAGCAAGCATCTATGACAGAGATACAGTCCAATCACCAGTTTATATGTTTTGGGGGGACATGTGTATATGGGGGTCTGTTCTCTCACTGTGTTTTGAGGCAGGGTCTTTGCAGGTTTTTGTCACTTAGCATACTGGCCCTGAGCTTCTGGTAGAGCCTCCTGTCTCTGTCTCCCATCTTGCTGTGGGACTACTGGGATGAGAGTTGAATGCTACCACATCTGTCTTTTAATGTGGGTACCAGGGGTCAAACTCAACCCTACTAGGCTTTCTTTTGGGGTAAATGCTTTACCTGCTGAGGAACTTCCTAGCCCCTCTAGTTCTTTGAATGTCAAAACTATCAGCCTATTTGTGGGCACTTATCGGAGCAGTTTTGTAAGATAGTCTAGAGTAATGAGAGTAATGAGCCCATTGGTTTTTAGGTACCTGCTGCTAAGTCTGAGGACCTATTCAGTCCCTAGGACTTGAGTGATGGCAGGAGAGAACTAACTCCACGAGCTGTCCTCTGACCTCACGTGTCTTGCTGTAGCATTGCCCCCAAATAAATAAATGAAATGAAAAAGAAATCTTTTAAAAAGATGTTATATTTGAGGCAGGTGTATCCTAGCACTTGGTATTGCCATAAATTTAAGGACAGAGTAAGTTTCAGGGGAGCCAGGGCCATAGAGTAAGACCTTGTCTCAAAAAACATAAGACAAAACCCCCAAACAAACAAAGAGATGGTGAGAGTCCTTCACCATTTGAAGGCATAATTGTTAAAATTGCCTTCAGTGAGGTGTATGGTTTACACACAATAAATTTAGTTTTGTTAAGTTTTGACAACAGCTGTGACCACAGTAAAAAAGATTTCCAAGGCCTGCAGCAGCAGCTGGCCTGTTGAAAGCCTGCTGCTCACAGTGTTGTGCTGACTGCCCTGCTGGAGGACAGGTCCCTTTGACTGGCCTTCTTTCTGTTAAAGCTGTGCTGTGGGGCAGCGGTGTCTCCTGTGGTTCTGTAGGATTTGTTGGAGAGCCTGAGGCTCACATGGAGGAATCTTAACAGTGCTTTACACGTCCTAATTAGTCACACAGTATTCCTAATCCAGGGATGTGTGGCTGGAGACCTTAGGTCAGCCTACTTCCTTGGTGCCTTCCAGCTCCTCCATTCCCTGATCACCTTCGTTTCAAAGCAGATACCCTGAGAGCCGTCTGTGTAGTTTAAGAGACTATTCTTTGTCTCTGTTGGTGATGTTTTTTTCTCTCAAATTGTTTTCTGTTAACATGATGAAACCATATTGACTAGGGGAAGTGGCTTGTTAACTGATGGCTAATTTTTATCCTAGTGCTGTCTCCTGTCTGAGTTGGCATGGTTGTGCCTCATTCTTTGCTAGTCAGTCCAGTGGCTGCCACTGAGCTAGCCTCTTGATTTAACTGATGTTCTTAGATGGATTATGCATGCCTTTCTTGACTTGTGTTGCCTTTTCTAG
Seq C2 exon
GTGGAAGACATTAGAAACTCATGATGTTGTAATAGAGTGTGCCAAAATCTCTCTGGACCCTACAGAAGCCTCGTATGAAGATGGCTATTCTGTGTCACACCAGCTCTCTGCTTGCTTCCCTTACCGTTCAGCTGATGTCACCACCAGCCCTTATGTGGACACACAGAATAGCTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812-Tsc1:NM_022887:8
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.120 A=NA C2=0.158
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(3.4=100)
A:
NA
C2:
PF043887=Hamartin=FE(13.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: