Special

MmuINT0170586 @ mm9

Intron Retention

Gene
ENSMUSG00000020099 | Unc5b
Description
unc-5 homolog B (C. elegans) [Source:MGI Symbol;Acc:MGI:894703]
Coordinates
chr10:60231856-60235159:-
Coord C1 exon
chr10:60234926-60235159
Coord A exon
chr10:60232006-60234925
Coord C2 exon
chr10:60231856-60232005
Length
2920 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGG
5' ss Score
8.76
3' ss Seq
TCCGTCTGCCCCACCTACAGGAG
3' ss Score
8.96
Exon sequences
Seq C1 exon
GAGGTGGTGACCTTGGATGAGGAGACCCTCAACACACCCTGCTACTGCCAGCTGGAGGCTAAGTCCTGCCACATCCTGCTGGACCAGCTGGGTACCTACGTATTCATGGGCGAGTCCTACTCTCGCTCTGCAGTCAAGCGGCTCCAGCTGGCCATCTTCGCCCCAGCCCTCTGCACCTCCCTGGAGTATAGCCTCAGGGTCTACTGTCTGGAGGACACACCTGTAGCACTGAAG
Seq A exon
GTAGGGGCTTGTCAGGGCACGGCAGGGGCATCAGCACAGCCAATCAATTGGTTGTTAGAACCCTCCCCAGATGCGTGGTCCCTACAGGCTTCTTTCTGGCACCAGCCTCAGAACAGCAATGGACCCTCAGGCAGGCATGGAGGCCGCAGCTCCTAGGACTGGGCAGGAGGTGGGAGACAAGCAGGGGAATCTCTTTGAGAAGTCTGAGAGAGCGGACTTCAGGCCTAAGCCCTGGGTGACAAGTTGTCACTCTGGGTAGAAAAGAGGAAGGGCATTTCAGACCAACAGAGCGACCTTCTGCCGAGACAGGTGTGCGGCTCAGCGTCGTGAGCAGAGTAGGATGTGTGTACGAGTAGTCCTGTAAGAGTGGGGGGGGGGGCTGGAGAGATAGTAGCTTGTTAGCAAGCTCAGGTCATGCCTAGCAATCAGGATGCCGACCAGTGGTGAGGGGCCCAGCTATGGCAGACACCTGTTCACAGGTACTTTGTAGAATTCCCTATAGCTATGGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATAACAGGAACATTGGTGAACAAGAGGCAGAGGCAAGTTGGGAAGCTGGGGGTATGCCCCACATAGCAGGCAGTAGCAATGGCCAGGAGATGAGACTGGGCCTTGTGGGTGGTCAGTGAGATGGACAGACCAGGAACTGATGGGATGAGCTAGGAAAACCTGAGCTTCTAGCAGACACAGAAGAAAAGGCAGTGGAGACCGGAAGTGAGGGAAAGGATGGGCAGAGAGGAAGGGGGCTAACACTGGCTGATGTGGAGCCCAAGTGGGCGTCCCACCTGTCTGTCATACATGCCTCAAAGCCCGTGCCCCTTCCTTCCCCAACTCTGTCCCATTCCCAGGTCCCCGGTCTCATCCTAGCGTGAAAGGGAGGATATAGACTTGGCTCTCTTCTCCATCTTTCTTCCAGCCCTCTCAGAAGCCTCATGGCTCTCTCTGGCAAACCAGTGCCTCTTTCCAGCTCTGAGTTGTGGTCTCTCCCAGTCACTCTGTCTCTTGAGTCTCATGTGACTTTCTCAGGCTGCGTGCTGGGGACTGATGCAACCCAGATGAAAAGGCCCTGTGGGAGAAGGGCGTCCTCTGTGGGGCTGTATTACCCTGACATTCCAGGAGGCCTCCAAAAGGGGGGTGGTCACGGCTGGGAATTTTTTCCAGAAGGATCTTGTGGCACTGGTATTGGCTGCTGTCCATCTGAGCCAGAGGGTGGTGTGAAGATCAACAGGGAAGTCACCACATTCTGGCTCAGTTGCGTTCTTTTAATTGTTCAAGCCCTGTCTATTCACCCGTCCATCTGCCCTCTACCTTTTCACTCATTGTGGTAATAAGTAATACACTTGCACAGTAAACAGCCAGTTGTTCACTCAGCCATTCTCTTCGCTCGTATGTCTTTCCTTCAAATGACCTTCTATTCATATACCTGTCATTTGTGTATCTATCTGTTTATGCTTACCCACACATCCATCCAATGATCTAGCCATCCATCATCCATCCATCATGTTACAGTAGTTGGCTAATCCTCTCTAATCTCCCGGGCAGATAGTGAGGAACTCACCCCAATGATCTGGATTCTTGAATGGAAGGCACGTGCGCGCACACACACACACACACACACAGCCTTATATCTAATATGCCTTAAACAGCTCAATGGCTGGGCACTTCCAGACCTCCCAGCGGCTAACCCACTTACCCCTCTGATATTCCTGAATTACTACTTTCTAAAACCTGTGTCCCATCTTGGCCTTCCCAGGTGCAGACCTATCGCCCACCTGGGTTTTGATCCCCGACTCTCACATGCTGGCTGTCTCTCTGTCTTATTTCTCACGCCTGATCCTTCTGCTTCCCCAGCATGGGGTTCTGCCTTTTTCTCTCTCTCCTGTGCCTCTTGGCCAGGAATCCTAAAGTCCTGCTTCTGTCTCACTGCCCAGCCATTATATCAATCAAAGCCAACTGGGACCAGGGACCCTCAGCATCCTACCTGTAGGTGTGTGAATTCCCATTTAATTTTGGGAACCCAGTTAACATAATACAAGCAATAAACCATATTCACAATACTATCATTCATCCATCGATCCATCTACCCATTCATCCATTATCCACCCATCTATCCATTCATCCATCCATCCACCTACCCACCCACCCATCCATCCATCCATCCATCCTCCATCCAACATCCATCTATCCATCCATCCATCCATCCATCCATCCATCCATCATCTTTGTGTTCTCCATCCTTCCAGCAGACCCCTGTCAGTATCCTTCTATACATCTAACCCATCTATCTAATTCTCCTTCCAAGTTCTTGTTACCCACACATATGTTCTCTGTGTATCTACCTATCCCCCTGTCCGCCCATGTGTCATCCATCCAGTTTATTGTCTATCTACTTAGCCATCCCATCAATTCATTTATCCAGCCACCAGAAATCCATTCATGAATCCCATCCATCCATCTATCCATCCACTTCCCTATTAATCTGTCTTTTAGCTTTCCATGTTATTGGTCAGTCTGTCTGTCTGTCTAGCTATCCACCTAGCCACAGCTTTCCCATTCATCCATTGGTGTATCTGTCCAGCCATTCATCGGAAACACCTTCTTAGCTGGATCAGACGGGTCTGGCCCCAGACCAGCAACTTGAAATATAAAAGAGGGGCTGGAGAGATGGCTCAGCGGTTAAGAGCACTGACTGCTCTTCCAGAGGCCCTGAGTTCAATCCCCAGCAACCACATGGTGGCTCACAACCATCTGTAATGGGATCTGATGTCATGTCTGAAGACAGCAACAATGTACTCACACATAAAATAAATAAAAAATCTTAAAAAAAAAAAATATAAAAGAGCCATATGCCAAGGGTAACAAGTCCTTCCGTCTGCCCCACCTACAG
Seq C2 exon
GAGGTCCTGGAGCTGGAGAGGACTCTGGGTGGCTACTTGGTGGAGGAGCCCAAGCCTTTGCTCTTTAAGGACAGTTACCACAACCTACGCCTCTCCCTCCATGACATCCCCCATGCCCACTGGAGGAGCAAACTACTGGCCAAGTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020099-Unc5b:NM_029770:13
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF094705=Telethonin=FE(66.4=100)

							
A:
NA

							
C2:
PF094705=Telethonin=PD(15.5=36.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000077080





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000101098
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:71293934-71295810 
ALTERNATIVE
HsaINT0177864
(UNC5B)
Human
(hg19)
chr10:73053691-73055567 
ALTERNATIVE
HsaINT0177864
(UNC5B)
Rat
(rn6)
chr20:30346113-30349380 
LOW PSI
RnoINT0160602
(Unc5b)
Cow
(bosTau6)
chr28:27594428-27596284 
LOW PSI
BtaINT0157557
(UNC5B)
Chicken
(galGal4)
chr6:11357834-11358447 
ALTERNATIVE
GgaINT0042394
(UNC5B)
Chicken
(galGal3)
chr6:12869089-12869702 
LOW PSI
GgaINT0042394
(UNC5B)
Zebrafish
(danRer10)
chr13:29086455-29086541 
LOW PSI
DreINT0171856
(unc5b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"