Special

MmuINT0179483 @ mm9

Intron Retention

Gene
ENSMUSG00000071291 | Zfp58
Description
zinc finger protein 58 [Source:MGI Symbol;Acc:MGI:99205]
Coordinates
chr13:67594943-67595665:-
Coord C1 exon
chr13:67595539-67595665
Coord A exon
chr13:67595039-67595538
Coord C2 exon
chr13:67594943-67595038
Length
500 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
TTCTCTTTTCCTCCAAACAGGTC
3' ss Score
12.91
Exon sequences
Seq C1 exon
GAAATGCTGTCATTCTGGGATGTGGCCATTGATTTTTCTCCAGAAGAGAGAGAATGCCTGGAGCCTGATCAGTGGGATCTGTACAGGGACGTGATGCTGGAGAATTACAGCCATCTGGATTTCCTGG
Seq A exon
GTGAGGATCATGTCCCCTTTGAATTCTTATTTCACTGTCAACGCGTTTCTTCCTCTGTACATTATCTCACACAAGCTTATGTTTTCCCACAGCACGTTTCATCTTCTTAGTTTTAAAGAAAAATTAGGGAATGTGCTTAGGCGGGAAACACTGCTTTCTCTTTTGTGTGTTTAGCCTGTCTGTGTTGGTTGAATGCATCCTTCTTCACAGAAGTGGGAATGTTAGAAACACTGTTTCAGTAGGCATGTACCTTACATAGAAAAAAAACAAAGTTTCACAATTTAATTTTAATGCCTTTCCCTTTAAATTAAACTCAGAATCTGGACACTGTATCTTCCTTCTCATAATGTAATGATCCTGTCAGAAGACATTTAAGGAACTAATTGTCTGTAGTCATTTATTTCAGCATCTCTTTCCTTACAAACACAGCGCTGAAAGGGACATGCCCACTCCCAGGAGAAGGACACTTGAACAATCTTGTTCTCTTTTCCTCCAAACAG
Seq C2 exon
GTCTTGCTCTCTCTAAGCCATTCCTGGTGACATTTCTGGAGCAAAGACAAGGGCCTTGGGACGTGAAGAGACAAGCAGCAGCCGCTGTGCACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000071291-Zfp58:NM_001007575:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion (1st CDS intron)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.061
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0135222=KRAB=WD(100=97.6)

							
A:
NA

							
C2:
PF0135222=KRAB=PD(0.1=0.0),PF054957=zf-CHY=PU(1.4=3.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000075487





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000089108, ENSMUSP00000129177, ENSMUSP00000132285
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr7:64441861-64442367 
HsaINT0186172
(ZNF117)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr18:60653743-60654072 
Chicken
(galGal4)
chr16:206560-206998 
HIGH PSI
GgaINT1004613
([1])
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGCTGTCATTCTGGGATGTGG

				
R: 
GGCTGCTGCTTGTCTCTTCAC

				
Band lengths: 
206-706

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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