RnoEX0025181 @ rn6
Exon Skipping
Gene
ENSRNOG00000054172 | Ctnnb1
Description
catenin beta 1 [Source:RGD Symbol;Acc:70487]
Coordinates
chr8:129618532-129619434:+
Coord C1 exon
chr8:129618532-129618785
Coord A exon
chr8:129618908-129619146
Coord C2 exon
chr8:129619233-129619434
Length
239 bp
Sequences
Splice sites
3' ss Seq
CCTCTCCACCCTTATTCTAGGTG
3' ss Score
10.76
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
Exon sequences
Seq C1 exon
ACATTGACGGTCAGTACGCCATGACTCGGGCTCAGAGGGTCCGAGCTGCCATGTTCCCTGAGACACTAGATGAGGGCATGCAGATCCCATCCACGCAGTTTGATGCCGCTCATCCCACTAATGTCCAGCGCTTGGCTGAACCGTCACAGATGCTGAAACATGCAGTTGTCAATTTGATTAACTATCAGGATGACGCGGAACTTGCCACCCGTGCAATTCCTGAGCTGACCAAACTGCTAAATGACGAGGACCAG
Seq A exon
GTGGTCGTTAATAAAGCTGCTGTTATGGTTCACCAGCTTTCCAAAAAGGAAGCTTCCAGACACGCCATCATGCGCTCCCCTCAGATGGTGTCTGCCATAGTGCGCACCATGCAGAATACAAATGACGTAGAAACAGCCCGTTGTACCGCTGGGACCCTACACAACCTTTCCCACCATCGAGAGGGCTTGTTGGCCATCTTTAAATCTGGCGGCATCCCAGCGCTGGTGAAAATGCTTGG
Seq C2 exon
GTCGCCAGTGGATTCCGTACTGTTCTACGCCATCACCACGCTGCATAATCTCCTGCTACATCAGGAAGGAGCTAAAATGGCAGTGCGCCTAGCTGGTGGGCTGCAGAAAATGGTTGCTTTGCTCAACAAAACAAACGTGAAGTTCTTGGCTATTACGACAGACTGCCTTCAGATCTTAGCTTACGGCAATCAGGAAAGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000054172-'3-9,'3-7,4-9
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.388 A=0.100 C2=0.000
Domain overlap (PFAM):
C1:
PF136461=HEAT_2=PU(46.1=55.3)
A:
PF136461=HEAT_2=PD(52.0=66.2),PF0051418=Arm=PU(51.2=26.2)
C2:
PF0051418=Arm=PD(46.3=27.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCCATGTTCCCTGAGACAC
R:
CGCACTGCCATTTTAGCTCCT
Band lengths:
296-535
Functional annotations
There are 1 annotated functions for this event
PMID: 11533658
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, glutathione s tranferase tag, phosphatase assay, pull down. ELM ID: ELMI001964; ELM sequence: MLGSPV; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]