DreEX0024841 @ danRer10
Exon Skipping
Gene
ENSDARG00000014571 | ctnnb1
Description
catenin (cadherin-associated protein), beta 1 [Source:ZFIN;Acc:ZDB-GENE-980526-362]
Coordinates
chr16:6293350-6296429:-
Coord C1 exon
chr16:6296176-6296429
Coord A exon
chr16:6295853-6296091
Coord C2 exon
chr16:6293350-6293551
Length
239 bp
Sequences
Splice sites
3' ss Seq
TGTTCTTCTATCCTCATCAGGTG
3' ss Score
9.35
5' ss Seq
CGGGTTAGT
5' ss Score
4.94
Exon sequences
Seq C1 exon
ACATCGATGGTCAATACGCCATGACCAGAGCCCAGAGAGTCCGGGCGGCCATGTTCCCGGAGACTCTCGATGAGGGCATGCAGATACCTTCCACACAGTTCGACTCTGCGCATCCCACCAATGTCCAGCGCCTGGCTGAGCCCTCGCAGATGCTCAAACATGCCGTGGTCAACCTCATCAACTACCAGGACGACGCAGAGCTGGCCACTCGTGCCATTCCAGAGCTCACCAAACTACTGAACGACGAGGATCAG
Seq A exon
GTGGTGGTTAATAAGGCAGCTGTGATGGTGCACCAGCTCTCCAAGAAAGAGGCCTCTCGTCACGCCATCATGCGCTCCCCACAGATGGTATCGGCCATTGTGAGGACCATGCAGAACACTAATGATGTAGAAACAGCCCGTTGCACCTCTGGCACCCTACACAATCTTTCCCACCACAGAGAAGGACTGCTTGCCATCTTTAAATCAGGAGGCATCCCTGCCCTCGTCAAAATGCTCGG
Seq C2 exon
CTCCCCTGTGGACTCTGTGCTGTTTTACGCTATTACGACTCTACACAACCTGCTACTGCACCAAGAAGGAGCCAAGATGGCTGTTCGACTGGCCGGAGGCCTGCAGAAAATGGTGGCCTTGTTAAACAAAACAAACGTCAAATTCCTCGCCATCACGACAGACTGCCTTCAGATTCTGGCATACGGCAATCAGGAAAGCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000014571-'12-10,'12-9,13-10
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.412 A=0.138 C2=0.000
Domain overlap (PFAM):
C1:
PF136461=HEAT_2=PU(46.5=55.3)
A:
PF136461=HEAT_2=PD(51.5=65.0),PF0051418=Arm=PU(51.2=26.2)
C2:
PF0051418=Arm=PD(46.3=27.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGCATGCAGATACCTTCCAC
R:
ACAAGGCCACCATTTTCTGCA
Band lengths:
303-542
Functional annotations
There are 1 annotated functions for this event
PMID: 11533658
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, glutathione s tranferase tag, phosphatase assay, pull down. ELM ID: ELMI001964; ELM sequence: MLGSPV; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]