BtaEX6093582 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000016420 | CTNNB1
Description
Bos taurus catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), mRNA. [Source:RefSeq mRNA;Acc:NM_001076141]
Coordinates
chr22:13876889-13877803:+
Coord C1 exon
chr22:13876889-13877142
Coord A exon
chr22:13877274-13877512
Coord C2 exon
chr22:13877602-13877803
Length
239 bp
Sequences
Splice sites
3' ss Seq
TTAATTCTTGTATATTATAGGTG
3' ss Score
9.11
5' ss Seq
CGGGTAAGA
5' ss Score
9.84
Exon sequences
Seq C1 exon
ATATTGATGGACAGTATGCAATGACTCGAGCTCAGAGGGTGAGAGCTGCTATGTTCCCTGAGACGCTAGATGAGGGCATGCAGATCCCATCTACACAGTTTGATGCCGCTCATCCCACTAACGTCCAGCGTCTGGCTGAACCATCACAGATGCTGAAACATGCAGTTGTAAACTTAATTAACTATCAAGATGATGCAGAACTTGCCACACGTGCAATCCCTGAATTGACAAAACTGCTGAATGATGAGGACCAG
Seq A exon
GTGGTGGTTAATAAGGCTGCAGTTATGGTCCATCAGCTTTCTAAAAAGGAAGCTTCGAGACACGCCATCATGCGTTCTCCTCAGATGGTGTCTGCTATCGTACGCACCATGCAGAACACAAATGACGTGGAGACAGCTCGCTGCACTGCTGGGACCTTGCACAATCTTTCCCACCATCGTGAGGGCTTGCTGGCCATCTTTAAATCTGGGGGCATTCCTGCCCTGGTGAAGATGCTCGG
Seq C2 exon
TTCACCAGTGGATTCTGTATTGTTTTATGCCATTACAACTCTCCACAACCTTTTATTGCATCAGGAAGGAGCTAAAATGGCCGTGCGTTTAGCTGGCGGGCTGCAGAAAATGGTTGCCTTGCTCAACAAAACGAATGTTAAATTCTTGGCTATTACAACAGATTGTCTTCAGATTCTAGCTTATGGCAATCAAGAAAGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000016420-'17-12,'17-11,18-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.388 A=0.100 C2=0.000
Domain overlap (PFAM):
C1:
PF136461=HEAT_2=PU(46.1=55.3)
A:
PF136461=HEAT_2=PD(52.0=66.2),PF0051418=Arm=PU(51.2=26.2)
C2:
PF0051418=Arm=PD(46.3=27.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCTATGTTCCCTGAGACGC
R:
ACGGCCATTTTAGCTCCTTCC
Band lengths:
293-532
Functional annotations
There are 1 annotated functions for this event
PMID: 11533658
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, glutathione s tranferase tag, phosphatase assay, pull down. ELM ID: ELMI001964; ELM sequence: MLGSPV; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]