DreEX0024842 @ danRer10
Exon Skipping
Gene
ENSDARG00000014571 | ctnnb1
Description
catenin (cadherin-associated protein), beta 1 [Source:ZFIN;Acc:ZDB-GENE-980526-362]
Coordinates
chr16:6291532-6296091:-
Coord C1 exon
chr16:6295853-6296091
Coord A exon
chr16:6293350-6293551
Coord C2 exon
chr16:6291532-6291676
Length
202 bp
Sequences
Splice sites
3' ss Seq
TATTGCTGTGGTCTCTTCAGCTC
3' ss Score
7.76
5' ss Seq
AAAGTAAGA
5' ss Score
6.91
Exon sequences
Seq C1 exon
GTGGTGGTTAATAAGGCAGCTGTGATGGTGCACCAGCTCTCCAAGAAAGAGGCCTCTCGTCACGCCATCATGCGCTCCCCACAGATGGTATCGGCCATTGTGAGGACCATGCAGAACACTAATGATGTAGAAACAGCCCGTTGCACCTCTGGCACCCTACACAATCTTTCCCACCACAGAGAAGGACTGCTTGCCATCTTTAAATCAGGAGGCATCCCTGCCCTCGTCAAAATGCTCGG
Seq A exon
CTCCCCTGTGGACTCTGTGCTGTTTTACGCTATTACGACTCTACACAACCTGCTACTGCACCAAGAAGGAGCCAAGATGGCTGTTCGACTGGCCGGAGGCCTGCAGAAAATGGTGGCCTTGTTAAACAAAACAAACGTCAAATTCCTCGCCATCACGACAGACTGCCTTCAGATTCTGGCATACGGCAATCAGGAAAGCAAA
Seq C2 exon
CTTATCATTCTGGCCAGCGGAGGCCCACAGGCTTTGGTCAACATCATGAGGACATACACCTATGAGAAGCTGTTATGGACGACCAGTCGAGTGCTCAAGGTGTTGTCAGTGTGCTCCAGTAACAAACCTGCCATTGTGGAGGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000014571-'13-13,'13-10,14-13
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.138 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF136461=HEAT_2=PD(51.5=65.0),PF0051418=Arm=PU(51.2=26.2)
A:
PF0051418=Arm=PD(46.3=27.9)
C2:
PF0051418=Arm=PU(26.8=22.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTCTCCAAGAAAGAGGCCT
R:
CGACTGGTCGTCCATAACAGC
Band lengths:
294-496
Functional annotations
There are 1 annotated functions for this event
PMID: 11533658
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, glutathione s tranferase tag, phosphatase assay, pull down. ELM ID: ELMI001964; ELM sequence: MLGSPV; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]