MmuEX6069909 @ mm10
Exon Skipping
Gene
ENSMUSG00000006932 | Ctnnb1
Description
catenin (cadherin associated protein), beta 1 [Source:MGI Symbol;Acc:MGI:88276]
Coordinates
chr9:120951267-120953003:+
Coord C1 exon
chr9:120951267-120951505
Coord A exon
chr9:120951586-120951787
Coord C2 exon
chr9:120952859-120953003
Length
202 bp
Sequences
Splice sites
3' ss Seq
AAAGGCTCTCCTCTTCCCAGGTC
3' ss Score
8.29
5' ss Seq
AAGGTAGAG
5' ss Score
6.38
Exon sequences
Seq C1 exon
GTGGTAGTTAATAAAGCTGCTGTTATGGTCCATCAGCTTTCCAAAAAGGAAGCTTCCAGACATGCCATCATGCGCTCCCCTCAGATGGTGTCTGCCATTGTACGCACCATGCAGAATACAAATGATGTAGAGACAGCTCGTTGTACTGCTGGGACTCTGCACAACCTTTCTCACCACCGCGAGGGCTTGCTGGCCATCTTTAAGTCTGGTGGCATCCCAGCGCTGGTGAAAATGCTTGG
Seq A exon
GTCACCAGTGGATTCTGTACTGTTCTACGCCATCACGACACTGCATAATCTCCTGCTCCATCAGGAAGGAGCTAAAATGGCAGTGCGCCTAGCTGGTGGACTGCAGAAAATGGTTGCTTTGCTCAACAAAACAAACGTGAAATTCTTGGCTATTACAACAGACTGCCTTCAGATCTTAGCTTATGGCAATCAAGAGAGCAAG
Seq C2 exon
CTCATCATTCTGGCCAGTGGTGGACCCCAAGCCTTAGTAAACATAATGAGGACCTACACTTATGAGAAGCTTCTGTGGACCACAAGCAGAGTGCTGAAGGTGCTGTCTGTCTGCTCTAGCAACAAGCCGGCCATTGTAGAAGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000006932-'37-24,'37-20,39-24
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.108 A=0.002 C2=0.024
Domain overlap (PFAM):
C1:
PF136461=HEAT_2=PD(52.0=66.2),PF0051418=Arm=PU(51.2=26.2)
A:
PF0051418=Arm=PD(46.3=27.9)
C2:
PF0051418=Arm=PU(26.8=22.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTGCCATTGTACGCACCAT
R:
CTTCTACAATGGCCGGCTTGT
Band lengths:
292-494
Functional annotations
There are 1 annotated functions for this event
PMID: 11533658
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, glutathione s tranferase tag, phosphatase assay, pull down. ELM ID: ELMI001964; ELM sequence: MLGSPV; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types