RnoEX0078554 @ rn6
Exon Skipping
Gene
ENSRNOG00000005018 | Scn2a
Description
sodium voltage-gated channel alpha subunit 2 [Source:RGD Symbol;Acc:3632]
Coordinates
chr3:51789816-51798933:+
Coord C1 exon
chr3:51789816-51790295
Coord A exon
chr3:51791368-51791451
Coord C2 exon
chr3:51798813-51798933
Length
84 bp
Sequences
Splice sites
3' ss Seq
ACCATTCTTACTTCTCACAGGGG
3' ss Score
8.26
5' ss Seq
CAGGTTACC
5' ss Score
-1.62
Exon sequences
Seq C1 exon
GTCCTGAACCTCTTCTTGGCCTTGCTCCTCAGTTCTTTCAGCTCAGACAACCTGGCTGCCACAGATGACGATAACGAAATGAACAACCTCCAGATAGCCGTGGGAAGGATGCAGAAGGGAATTGATTTTGTTAAAAGGAAGATACGTGAATTCATTCAGAAAGCCTTTGTCAGAAAGCAGAAAGCTTTAGATGAAATCAAACCGCTGGAAGATCTGAATAACAAGAAAGACAGTTGTATCTCCAACCACACGACCATAGAAATAGGCAAGGACCTCAATTACCTCAAAGATGGAAACGGGACGACCAGTGGCATAGGCAGCAGTGTGGAGAAGTATGTGGTAGATGAGAGTGATTACATGTCGTTCATAAACAACCCCAGCCTCACCGTGACTGTGCCCATCGCCCTTGGAGAGTCTGACTTTGAAAACTTAAACACGGAAGAATTCAGTAGTGAGTCAGATATGGAAGAAAGCAAGGAG
Seq A exon
GGGTGAGACCAAGCTGGAGCCATCAAGAAAGCCGCTCTGGTGTTTTTTAAGCAGCCAGAGGCTCGAGCCACCACTTTTACCCAG
Seq C2 exon
AAATTGAATGCAACTAGCTCATCTGAGGGCAGTACGGTTGATATAGGCGCTCCGGCAGAGGGAGAGCAGCCAGAGGCCGAACCGGAAGAATCGCTTGAACCGGAAGCGTGTTTCACAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000005018_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.115 A=1.000 C2=0.780
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.0),PF065128=Na_trans_assoc=PU(61.3=85.0)
A:
PF065128=Na_trans_assoc=PD(0.1=0.0)
C2:
PF065128=Na_trans_assoc=FE(18.0=100)
Main Inclusion Isoform:
ENSRNOT00000007069fB12982
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCGCCCTTGGAGAGTCTGA
R:
TCAAGCGATTCTTCCGGTTCG
Band lengths:
180-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]