RnoEX6001821 @ rn6
Exon Skipping
Gene
ENSRNOG00000020871 | Ltbp4
Description
latent transforming growth factor beta binding protein 4 [Source:RGD Symbol;Acc:1307033]
Coordinates
chr1:84122015-84123572:-
Coord C1 exon
chr1:84123306-84123572
Coord A exon
chr1:84122959-84123030
Coord C2 exon
chr1:84122015-84122143
Length
72 bp
Sequences
Splice sites
3' ss Seq
ATCTTTCCTTCTATGTACAGCTG
3' ss Score
8.76
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
GCACGTTCCCAGGCTCGCAGCCCCAAGCACCTGCCAGCCCCAGTCTTCCAGCCAGGCCTCCCGCCCCTCCCCCACCTCGAAGACCCAGTCCTCCCAGGCAGGGTCCCGTGAGCAGTGGGCGTCGTGAGTGCTACTTTGACACGGCAGCTCCAGATGCGTGTGACAATATCTTGGCTCGTAACGTGACGTGGCAGGAGTGCTGCTGTACTGTGGGAGAAGGCTGGGGCAGCGGGTGCCGCATCCAGCAGTGCCCGGGCACGGAGACAG
Seq A exon
CTGAATACCAGTCATTGTGTCCTCACGGCCGGGGCTACCTAGTGCCCAGTGGAGACCTGAGTGCCCGGAGAG
Seq C2 exon
ATGTGGATGAATGCCAACTCTTCCAGGACCAGGTGTGCAAGAGCGGAGTGTGTGTGAACACTGCCCCAGGCTACTCTTGCTATTGCAACAACGGCTTCTACTATCATGCGCACAGGCTGGAATGCGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000020871-'39-36,'39-34,41-36=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.400 A=0.040 C2=0.000
Domain overlap (PFAM):
C1:
PF0068312=TB=PU(86.4=42.2)
A:
PF0068312=TB=PD(11.4=20.0),PF0764510=EGF_CA=PU(0.1=0.0)
C2:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGCTACTTTGACACGGCAG
R:
ACACCTGGTCCTGGAAGAGTT
Band lengths:
177-249
Functional annotations
There are 1 annotated functions for this event
PMID: 11683420
LTBP-4delta8-Cys3rd (skipping of both exons) does not bind TGF-beta and it was found to be expressed in the same tissues as the full length LTBP-4
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]