RnoEX6006662 @ rn6
Exon Skipping
Gene
ENSRNOG00000021057 | Osbp
Description
oxysterol binding protein [Source:RGD Symbol;Acc:1308069]
Coordinates
chr1:228407446-228408471:+
Coord C1 exon
chr1:228407446-228407644
Coord A exon
chr1:228407880-228407982
Coord C2 exon
chr1:228408417-228408471
Length
103 bp
Sequences
Splice sites
3' ss Seq
TGAGGCTTTTCTTTTTGTAGAGC
3' ss Score
7.7
5' ss Seq
CAAGTAAGC
5' ss Score
7.47
Exon sequences
Seq C1 exon
GCCTGCAGAGATTTCCTCATGTTAGCCCAGACGCATAGTAAGAAGTGGCAGAAGTCCCTGCAGTATGAACGGGACCAGCGTATCCGACTGGAAGAAACTCTTGAGCAGCTGGCGAAGCAGCACAATCACCTGGAGAGAGCCTTCCGGGGAGCCACAGTGCTGCCAGCAAACACTCCGGGCAGCACTGGGTCTGGTAAAG
Seq A exon
AGCAGTGCTGTTCTGGCAAAGGGGACATGAGCGATGAAGATGACGAGAACGAATTCTTTGACGCACCAGAGATTATCACCATGCCTGAAAACTTGGGCCACAA
Seq C2 exon
ACGTACTGGTAGCAATATCAGTGGAGCCAGCAGTGACATCAGCCTTGATGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000021057-'16-6,'16-4,17-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.507 A=0.886 C2=0.789
Domain overlap (PFAM):
C1:
PF0247911=Herpes_IE68=PD(73.3=94.0)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTGCAGAGATTTCCTCATGT
R:
TCAAGGCTGATGTCACTGCTG
Band lengths:
247-350
Functional annotations
There are 1 annotated functions for this event
PMID: 12727870
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, confocal microscopy, glutathione s tranferase tag, green fluorescent protein tag, mutation analysis, pull down. ELM ID: ELMI001275; ELM sequence: EDDENEFFDAPE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]