RnoEX6015271 @ rn6
Exon Skipping
Gene
ENSRNOG00000007247 | A2ml1
Description
alpha-2-macroglobulin-like 1 [Source:RGD Symbol;Acc:1565709]
Coordinates
chr4:161881853-161885157:-
Coord C1 exon
chr4:161884929-161885157
Coord A exon
chr4:161884150-161884283
Coord C2 exon
chr4:161881853-161881961
Length
134 bp
Sequences
Splice sites
3' ss Seq
GGCCATTATTCCCTTTTTAGATT
3' ss Score
8.95
5' ss Seq
TAAGCAGAT
5' ss Score
-11.12
Exon sequences
Seq C1 exon
TTCCTCAGGCTCAACCAATGTTTCGTTCCTTGTCCCTGATACCATCACCCAGTGGCAGGCCAGCACCTTCTGTGTCAACGGCAATGCTGGGTTCGGCATTTCACCCAAAGTGTCCCTACAAATCTCCCAGCCCTTCTTCATGGAAGTTACCTCACCCTTTTCTGTTGTTCGAAGTGAACAGAGTGACCTCATTGTCACTGTCTTCAACTACCGGACTACATGTGTAGAG
Seq A exon
ATTTCTGTTCAGTTAGAAGCATCTGAGAATTATGAAGCAAGCATCAACACCCAGAGTAACACTGACAGTGAGGTCCTGCCGGCTGGAGAACAGAAAACGTATGTCTGGACCGTTACACCAAAAACACTGGGTAA
Seq C2 exon
AGTGGATATCACTGTAGTGGCTACATCCAAAAGAGTAGTGCCCTGCCCAAATGAATGCCATGAGGGGCAGATGTCAACTGGAAGGAACACTGTAGTTCAAAACCTTTAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000007247-'23-21,'23-19,24-21=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.244 C2=0.216
Domain overlap (PFAM):
C1:
PF0020717=A2M=FE(83.5=100)
A:
PF0020717=A2M=PD(4.4=8.9)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTGTGTCAACGGCAATGCT
R:
CTTCCAGTTGACATCTGCCCC
Band lengths:
246-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]