RnoEX6031947 @ rn6
Exon Skipping
Gene
ENSRNOG00000025053 | Lrp1
Description
LDL receptor related protein 1 [Source:RGD Symbol;Acc:1307535]
Coordinates
chr7:70846344-70847688:-
Coord C1 exon
chr7:70847598-70847688
Coord A exon
chr7:70847359-70847503
Coord C2 exon
chr7:70846344-70847215
Length
145 bp
Sequences
Splice sites
3' ss Seq
TGACTCCTGCCTCTCCCCAGGGC
3' ss Score
11.32
5' ss Seq
AAGGTACGC
5' ss Score
10.4
Exon sequences
Seq C1 exon
ATATGACCTCCATCCTGATCCCTCTGCTGCTGCTGCTCCTGCTGCTGCTGGTGGCAGGCGTGGTGTTCTGGTATAAGCGGCGAGTCCGAGG
Seq A exon
GGCTAAGGGCTTCCAGCACCAGCGGATGACCAATGGGGCCATGAATGTGGAAATCGGAAACCCTACCTACAAGATGTATGAAGGTGGAGAGCCCGACGATGTGGGGGGCCTCCTGGATGCTGATTTTGCCCTTGACCCTGACAAG
Seq C2 exon
CCTACCAACTTCACCAACCCAGTGTATGCCACGCTCTACATGGGGGGTCATGGCAGCCGCCACTCCCTGGCCAGCACGGACGAGAAGCGAGAACTGCTGGGCCGGGGACCTGAAGATGAGATAGGGGATCCCTTAGCATAGGGCCCTGCCCCAACGGACGTCCCCAGAAAGCCCCTGCCACACGAGTCTTTCAATGAGCCCTCTCCCCAGCCAGCCCTTCTCCGGCCCTGCCGGATGTACAAATGTAAAAATGAAGGAATTACTTTTTATATGTGAGTGAGCAAGCACAGTATTATCTCTTTGCATTTCCTTTCTGCCTGCTCCTCGGCATCCCCTCCCCCCATGCTGCCTTGAGGGGGCAGGGAGGGCTCTGTGGCTCAAAGGTATGAAGGAGTCCACATACGTTCCCTTACCCCGGGAAGCTGGCGGCACAGCCTCTCGCCTGTACAAGACACTCAACAGGGCTCCAGTGTCCCAGCTTTCCTTTCCTGGGGTTAGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000025053-'131-142,'131-141,132-142=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.367 C2=0.522
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATCCTGATCCCTCTGCTG
R:
CTTTCTGGGGACGTCCGTTG
Band lengths:
254-399
Functional annotations
There are 3 annotated functions for this event
PMID: 15115822
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, knock out, mutation analysis, pull down. ELM ID: ELMI001560; ELM sequence: EIGNPTYK; Overlap: FULL
PMID: 16382151
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, glutathione s tranferase tag, knock out, mutation analysis, pull down. ELM ID: ELMI001560; ELM sequence: EIGNPTYK; Overlap: FULL
PMID: 18381291
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, nuclear magnetic resonance. ELM ID: ELMI001543; ELM sequence: EIGNPTY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]