Special

FBgn0000581 @ dm6

Biotype
protein_coding
Gene Symbol
E(Pc)
Description
The gene Enhancer of Polycomb is referred to in FlyBase by the symbol DmelE(Pc) (CG7776, FBgn0000581). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 2R:11452043..11465270. Its molecular function is described by: histone acetyltransferase activity. It is involved in the biological process described with: dendrite guidance; regulation of transcription by RNA polymerase II; histone exchange; chromatin organization; histone acetylation. 25 alleles are reported. The phenotypes of these alleles manifest in: external sensory organ; external sensillum; tergum; adult neuron; posterior crossvein. The phenotypic classes of alleles include: phenotype; increased mortality; neuroanatomy defective; modifier of variegation. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:11452043-11465270:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 5'ss
0
NA
+
88.36
25.19
0
Alternative 5'ss
0
NA
+
11.49
26.47
0
Alternative 5'ss
5
chr2R:11452876-11452880
+
59.39
34.51
0
Alternative 5'ss
10
chr2R:11452876-11452885
+
19.74
18.54
0
Exon Skipping
182
chr2R:11455820-11456001
+
97.23
35.21
0
Intron Retention
1009
chr2R:11452384-11453392
+
58.25
67.79
0
Intron Retention
67
chr2R:11456921-11456987
+
5.03
100
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000120616 EPC1 1-to-2
Human hg38 ENSG00000135999 EPC2 1-to-2
Human hg19 ENSG00000120616 EPC1 1-to-2
Human hg19 ENSG00000135999 EPC2 1-to-2
Mouse mm10 ENSMUSG00000024240 Epc1 1-to-2
Mouse mm10 ENSMUSG00000069495 Epc2 1-to-2
Mouse mm9 ENSMUSG00000024240 Epc1 1-to-2
Mouse mm9 ENSMUSG00000069495 Epc2 1-to-2
Rat rn6 ENSRNOG00000014834 Epc1 1-to-2
Rat rn6 ENSRNOG00000029447 Epc2 1-to-2
Cow bosTau6 ENSBTAG00000001552 EPC1 1-to-2
Cow bosTau6 ENSBTAG00000018581 EPC2 1-to-2
Chicken galGal4 ENSGALG00000007169 EPC1 1-to-2
Chicken galGal4 ENSGALG00000012453 EPC2 1-to-2
Chicken galGal3 ENSGALG00000007169 EPC1 1-to-2
Chicken galGal3 ENSGALG00000012453 EPC2 1-to-2
Zebrafish danRer10 ENSDARG00000007485 epc2 1-to-3
Zebrafish danRer10 ENSDARG00000060054 epc1b 1-to-3
Zebrafish danRer10 ENSDARG00000101579 epc1a 1-to-3