Special

FBgn0003137 @ dm6

Biotype
protein_coding
Gene Symbol
Ppn
Description
The gene Papilin is referred to in FlyBase by the symbol DmelPpn (CG33103, FBgn0003137). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:28520665..28540324. Its molecular function is described by: serine-type endopeptidase inhibitor activity; peptidase activity; extracellular matrix structural constituent. It is involved in the biological process described with: extracellular matrix organization. 9 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval tracheal system; embryonic/larval somatic muscle; Malpighian tubule. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; lethal - all die before end of pupal stage; some die during embryonic stage; some die during pupal stage; partially lethal; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages.
Coordinates
chr3R:28520665-28540324:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
417
chr3R:28521815-28522231
-
75.1
98.79
0
Exon Skipping
171
chr3R:28525417-28525587
-
68.32
99.8
0
Exon Skipping
1034
chr3R:28524274-28525307
-
77.11
100
0
Exon Skipping
184
chr3R:28524034-28524217
-
78.61
100
0
Exon Skipping
195
chr3R:28523780-28523974
-
52.49
100
0
Exon Skipping
171
chr3R:28523527-28523697
-
56.72
100
0
Intron Retention
8339
chr3R:28531580-28539918
-
5.19
100
0
Intron Retention
2610
chr3R:28523261-28525870
-
3.68
21.94
0
Intron Retention
781
chr3R:28521701-28522481
-
6.48
37.14
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000185761 ADAMTSL5 1-to-1
Human hg19 ENSG00000185761 ADAMTSL5 1-to-1
Mouse mm10 ENSMUSG00000043822 Adamtsl5 1-to-1
Mouse mm9 ENSMUSG00000043822 Adamtsl5 1-to-1
Rat rn6 ENSRNOG00000009448 Papln 1-to-1
Cow bosTau6 ENSBTAG00000006662 1-to-2
Cow bosTau6 ENSBTAG00000046263 1-to-2
Chicken galGal4 ENSGALG00000024298 ADAMTSL5 1-to-1
Chicken galGal3 ENSGALG00000024298 ADAMTSL5 1-to-1
Zebrafish danRer10 ENSDARG00000052118 ADAMTSL5 1-to-1