Special

FBgn0010225 @ dm6

Biotype
protein_coding
Gene Symbol
Gel
Description
The gene Gelsolin is referred to in FlyBase by the symbol DmelGel (CG1106, FBgn0010225). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (3 unique). Gene sequence location is 3R:4235217..4241057. Its molecular function is described by: phosphatidylinositol-4,5-bisphosphate binding; protein binding; actin filament binding. It is involved in the biological process described with: barbed-end actin filament capping; actin filament polymerization; actin filament severing; actin polymerization or depolymerization. 7 alleles are reported. The phenotypes of these alleles manifest in: adult brain; mitochondrion. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable; size defective; partially lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed at stages throughout the larval period, during early pupal stages.
Coordinates
chr3R:4235217-4241057:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 5'ss
0
NA
+
74.43
100
0
Alternative 5'ss
135
chr3R:4236805-4236939
+
25.38
100
0
Intron Retention
685
chr3R:4236940-4237624
+
9.75
49.28
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Rat rn6 ENSRNOG00000004498 Scin 1-to-5
Rat rn6 ENSRNOG00000011446 Vill 1-to-5
Rat rn6 ENSRNOG00000015408 Vil1 1-to-5
Rat rn6 ENSRNOG00000018991 Gsn 1-to-5
Rat rn6 ENSRNOG00000050419 Avil 1-to-5