Special

FBgn0034013 @ dm6

Biotype
protein_coding
Gene Symbol
unc-5
Description
The gene unc-5 is referred to in FlyBase by the symbol Dmelunc-5 (CG8166, FBgn0034013). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:15340472..15368300. Its molecular function is described by: netrin receptor activity involved in chemorepulsion; netrin receptor activity. It is involved in the biological process described with 6 unique terms, many of which group under: multicellular organism development; anatomical structure morphogenesis; developmental process; regulation of locomotion; plasma membrane bounded cell projection morphogenesis. 29 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; cell projection; dorsal vessel primordium; visual system neuron; filopodium. The phenotypic classes of alleles include: increased mortality; cell migration defective; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages.
Coordinates
chr2R:15340472-15368300:+
Assembly
dm6

GENOMIC BROWSER[edit]

EXPRESSION VALUES[edit]

SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
318
chr2R:15361983-15362300
+
96.95
83.12
0
Intron Retention
296
chr2R:15357713-15358008
+
4.35
60.56
0
Intron Retention
288
chr2R:15358291-15358578
+
5.78
76.47
0
Intron Retention
1665
chr2R:15358750-15360414
+
6.97
63.27
0
Intron Retention
2212
chr2R:15362301-15364512
+
7.06
54.18
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000107731 UNC5B 1-to-5
Human hg38 ENSG00000113763 UNC5A 1-to-5
Human hg38 ENSG00000124602 UNC5CL 1-to-5
Human hg38 ENSG00000156687 UNC5D 1-to-5
Human hg38 ENSG00000182168 UNC5C 1-to-5
Human hg19 ENSG00000107731 UNC5B 1-to-5
Human hg19 ENSG00000113763 UNC5A 1-to-5
Human hg19 ENSG00000124602 UNC5CL 1-to-5
Human hg19 ENSG00000156687 UNC5D 1-to-5
Human hg19 ENSG00000182168 UNC5C 1-to-5
Mouse mm10 ENSMUSG00000020099 Unc5b 1-to-5
Mouse mm10 ENSMUSG00000025876 Unc5a 1-to-5
Mouse mm10 ENSMUSG00000043592 Unc5cl 1-to-5
Mouse mm10 ENSMUSG00000059921 Unc5c 1-to-5
Mouse mm10 ENSMUSG00000063626 Unc5d 1-to-5
Mouse mm9 ENSMUSG00000020099 Unc5b 1-to-5
Mouse mm9 ENSMUSG00000025876 Unc5a 1-to-5
Mouse mm9 ENSMUSG00000043592 Unc5cl 1-to-5
Mouse mm9 ENSMUSG00000059921 Unc5c 1-to-5
Mouse mm9 ENSMUSG00000063626 Unc5d 1-to-5
Rat rn6 ENSRNOG00000000567 Unc5b 1-to-5
Rat rn6 ENSRNOG00000011858 Unc5d 1-to-5
Rat rn6 ENSRNOG00000029071 Unc5c 1-to-5
Rat rn6 ENSRNOG00000046601 Unc5cl 1-to-5
Rat rn6 ENSRNOG00000059840 Unc5a 1-to-5
Cow bosTau6 ENSBTAG00000002084 UNC5C 1-to-5
Cow bosTau6 ENSBTAG00000002919 UNC5CL 1-to-5
Cow bosTau6 ENSBTAG00000010241 UNC5D 1-to-5
Cow bosTau6 ENSBTAG00000014270 UNC5B 1-to-5
Cow bosTau6 ENSBTAG00000014897 UNC5A 1-to-5
Chicken galGal4 ENSGALG00000001608 UNC5D 1-to-4
Chicken galGal4 ENSGALG00000004569 UNC5B 1-to-4
Chicken galGal4 ENSGALG00000012219 UNC5C 1-to-4
Chicken galGal4 ENSGALG00000018998 UNC5A 1-to-4
Chicken galGal3 ENSGALG00000001608 UNC5D 1-to-4
Chicken galGal3 ENSGALG00000004569 UNC5B 1-to-4
Chicken galGal3 ENSGALG00000012219 UNC5C 1-to-4
Chicken galGal3 ENSGALG00000018998 UNC5A 1-to-4
Zebrafish danRer10 ENSDARG00000033327 unc5b 1-to-6
Zebrafish danRer10 ENSDARG00000061541 unc5db 1-to-6
Zebrafish danRer10 ENSDARG00000087341 unc5c 1-to-6
Zebrafish danRer10 ENSDARG00000092722 unc5da 1-to-6
Zebrafish danRer10 ENSDARG00000099133 UNC5C (2 of 2) 1-to-6
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