Special

FBgn0260970 @ dm6

Biotype
protein_coding
Gene Symbol
CG42593
Description
The gene Ubr3 ubiquitin ligase is referred to in FlyBase by the symbol DmelUbr3 (CG42593, FBgn0260970). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:7935896..7953883. Its molecular function is described by: ubiquitin protein ligase activity; protein binding; zinc ion binding. It is involved in the biological process described with 6 unique terms, many of which group under: regulation of cellular process; positive regulation of biological process; regulation of cell death; cellular protein modification process; cell death. 26 alleles are reported. The phenotypes of these alleles manifest in: visual system; eye-antennal disc; cell; antennal segment; sensillum. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; phenotype; lethal - all die before end of prepupal stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chrX:7935896-7953883:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Intron Retention
70
chrX:7940425-7940494
+
4.52
61.29
0
Intron Retention
59
chrX:7940724-7940782
+
9.54
100
0
Intron Retention
60
chrX:7941196-7941255
+
11
74.81
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000144357 UBR3 1-to-1
Human hg19 ENSG00000144357 UBR3 1-to-1
Mouse mm10 ENSMUSG00000044308 Ubr3 1-to-1
Mouse mm9 ENSMUSG00000044308 Ubr3 1-to-1
Rat rn6 ENSRNOG00000008616 Ubr3 1-to-1
Cow bosTau6 ENSBTAG00000020296 UBR3 1-to-1
Chicken galGal4 ENSGALG00000009608 UBR3 1-to-3
Chicken galGal3 ENSGALG00000009608 1-to-3
Zebrafish danRer10 ENSDARG00000042508 ubr3 1-to-1