Special

FBgn0262732 @ dm6

Biotype
protein_coding
Gene Symbol
mbf1
Description
The gene multiprotein bridging factor 1 is referred to in FlyBase by the symbol Dmelmbf1 (CG4143, FBgn0262732). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 3L:16574436..16576871. Its molecular function is described by: protein-macromolecule adaptor activity; transcription coactivator activity; sequence-specific DNA binding; mRNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; central nervous system development; mRNA stabilization; open tracheal system development. 14 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; tormogen cell; presumptive embryonic/larval tracheal system; trichogen cell; presumptive embryonic/larval central nervous system. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; visible.
Coordinates
chr3L:16574436-16576871:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Intron Retention
100
chr3L:16574753-16574852
+
16.48
79.79
0
Intron Retention
210
chr3L:16574977-16575186
+
11.39
75.85
0
Intron Retention
369
chr3L:16575348-16575716
+
4.96
57.06
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000107223 EDF1 1-to-1
Human hg19 ENSG00000107223 EDF1 1-to-1
Mouse mm10 ENSMUSG00000015092 Edf1 1-to-1
Mouse mm9 ENSMUSG00000015092 Edf1 1-to-1
Rat rn6 ENSRNOG00000016272 Edf1 1-to-1
Cow bosTau6 ENSBTAG00000030302 EDF1 1-to-1
Zebrafish danRer10 ENSDARG00000009950 edf1 1-to-1