BtaEX0003426 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000019052 | ANK3
Description
Bos taurus ankyrin 3, node of Ranvier (ankyrin G) (ANK3), mRNA. [Source:RefSeq mRNA;Acc:NM_001105620]
Coordinates
chr28:15837748-15852823:-
Coord C1 exon
chr28:15852445-15852823
Coord A exon
chr28:15839428-15839511
Coord C2 exon
chr28:15837748-15837835
Length
84 bp
Sequences
Splice sites
3' ss Seq
CTTTATGCCACATCCTTTAGGGA
3' ss Score
7.32
5' ss Seq
AAAGTAATC
5' ss Score
0.63
Exon sequences
Seq C1 exon
CCCTGACCAGTGTAGAGATTCCATTACCTCCTATCTCAAAGGGGAGCCTGGAAAATTTGAAGCCAATGGAAGCCATGCAGAAGTCACTCCAGAAGCAAAGACAAAATCTTACTTTCCAGAATCCCAAAATGATGTAGGGAAACAGAGTGCAAAGGAAACCCTGAAACCAAAAATACAAGGATCTGGTCGTGTTGATGAACCAGCATCATCACTAGCAGCGTATCAGAAGGCTCTAGAAGAAACCAGCAAGTTTGTAATAGAAGAACCTAAACCCTGTGTGCCTGTCAGTATGAAAAAGATGAGTAGGACTTCTCCTGCAGATGGCAAGCCACGGCTTAACCTCCATGAAGAAGAGGGGTCCAATGGGTCTGAGCAGAAG
Seq A exon
GGAGAGGAAGCAAAAACCATTCCTGGTGAATCTGTCACAGAAGAACAGTTTACTGATGAAGAAGGCAACCTCATCACCAGAAAA
Seq C2 exon
GGAGAAGCTTATAAGATGAAGACGAAGAAAGAAATCCGTCAAGTGGAAAAGAAGAGCCATTCATAACAGTAAACGGTCAACCAACGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000019052_MULTIEX1-4/5=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.940 A=1.000 C2=0.905
Domain overlap (PFAM):
C1:
NO
A:
PF0053117=Death=PD(2.4=7.1)
C2:
NO
Main Inclusion Isoform:
ENSBTAT00000061228fB561
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTAAACCCTGTGTGCCTGTC
R:
GCTCTTCTTTTCCACTTGACGGA
Band lengths:
171-255
Functional annotations
There are 1 annotated functions for this event
PMID: 21223964
Ankyrins-G coimmunoprecipitated with plectin and filamin C from skeletal muscle tissue extracts. Muscle-specific OTBD domain (coordinated inclusion of MmuEX1003810, MmuEX1003809, MmuEX0004908) is required for ankyrin-G binding to plectin and filamin C. Isoforms are differentially expressed during myogenesis.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development