RnoEX0009389 @ rn6
Exon Skipping
Gene
ENSRNOG00000053288 | Ank3
Description
ankyrin 3 [Source:RGD Symbol;Acc:620157]
Coordinates
chr20:20454767-20471282:+
Coord C1 exon
chr20:20454767-20455145
Coord A exon
chr20:20469648-20469731
Coord C2 exon
chr20:20471197-20471282
Length
84 bp
Sequences
Splice sites
3' ss Seq
CTCTATGCCGCATCCTTTAGGGA
3' ss Score
7.4
5' ss Seq
AAAGTAATC
5' ss Score
0.63
Exon sequences
Seq C1 exon
CTCTGACCAGGTTCGGGATCCCATTACCTCATACCTCACAGGAGAAGCTGGGAAGTTCGAAGCAAACGGAAACCACGCAGAAGTCATTCCAGAAGCAAAGGCCAAGGCCTACTTTCCTGAATCCCAAAACGATATAGGGAAACAGAGCATCAAGGAGAACTTGAAACCAAAAACACACGGATGTGGTCGCGCTGAGGAACCAGTGTCGCCCCTCACAGCCTACCAGAAATCTCTAGAAGAAACCAGCAAGCTTGTCATAGAAGACGCACCTAAACCCTGTGTGCCTGTCGGCATGAAAAAGATGACCAGGACTCCGGCTGACGGCAAAGCCAGGCTCAACCTCCAGGAAGAGGAGGGGTCCGCCAGGTCAGAGCCTAAG
Seq A exon
GGAGAGGAAGCCAAAACCATCCCTGGTGAATCTGTCACAGAAGAGCAATTTACCGATGAAGAAGGCAACCTCATCACTAGAAAA
Seq C2 exon
CAGGGAGAAGGCTATAAGGTGAAAACAAAGAAGGAAATCCGGAATGTGGAGAAGAAAGCCCACTAGTGACGGTGACGTCAGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000053288_MULTIEX1-3/4=C1-C2
Average complexity
ME(1-3[100=100])
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.930 A=0.885 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTAAACCCTGTGTGCCTGTCG
R:
ACCGTCACTAGTGGGCTTTCT
Band lengths:
183-267
Functional annotations
There are 1 annotated functions for this event
PMID: 21223964
Ankyrins-G coimmunoprecipitated with plectin and filamin C from skeletal muscle tissue extracts. Muscle-specific OTBD domain (coordinated inclusion of MmuEX1003810, MmuEX1003809, MmuEX0004908) is required for ankyrin-G binding to plectin and filamin C. Isoforms are differentially expressed during myogenesis.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]