BtaEX6015447 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000007909 | NOTCH2
Description
notch 2 [Source:HGNC Symbol;Acc:HGNC:7882]
Coordinates
chr3:23470803-23471891:+
Coord C1 exon
chr3:23470803-23470945
Coord A exon
chr3:23471145-23471355
Coord C2 exon
chr3:23471795-23471891
Length
211 bp
Sequences
Splice sites
3' ss Seq
CTATCTCTCTGCACTTTCAGGTG
3' ss Score
11.1
5' ss Seq
CAAGTAAGA
5' ss Score
7.61
Exon sequences
Seq C1 exon
CTCTCAGGTATTTCTGGAGATTGACAACCGCCAGTGTGTTCAAGACTCAGACCAGTGCTTTAAGAACACAGACGCAGCCGCAGCTCTTCTGGCTTCTCACGCCATCCAGGGGACCCTGTCGTACCCACTTGTGTCTGTCGTCA
Seq A exon
GTGAATCTCTGACCCCAAAACCCACTCAGCTTCTCTATCTGCTTGCTGTTGCCGTTGTCATTATCTTGTTTATTATCCTCCTGGGGGTTATCATGGCAAAACGAAAGCGCAAGCATGGCTCCCTCTGGCTGCCTGAAGGTTTCACCCTTCGCCGTGACTCCAGCAACCACAAACGTCGTGAGCCAGTGGGCCAGGATGCTGTGGGACTCAA
Seq C2 exon
AAATCTTTCAGTGCAAGTCTCAGAGGCGAACCTAATTGGTTCTGGAACAAGTGAACACTGGGTCGATGATGAAGGGCCGCAGCCTAAGAAAGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000007909-'39-37,'39-36,40-37=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.183 C2=0.545
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(78.7=100)
A:
PF076847=NODP=PD(14.8=12.7)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCAGGTATTTCTGGAGATTGACA
R:
GGCTTTCTTAGGCTGCGGC
Band lengths:
236-447
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002958; ELM sequence: LWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]