RnoEX6010751 @ rn6
Exon Skipping
Gene
ENSRNOG00000018835 | Notch2
Description
notch 2 [Source:RGD Symbol;Acc:3188]
Coordinates
chr2:200308660-200309944:+
Coord C1 exon
chr2:200308660-200308802
Coord A exon
chr2:200308920-200309130
Coord C2 exon
chr2:200309848-200309944
Length
211 bp
Sequences
Splice sites
3' ss Seq
CCCTGTCTCTGAACTTTCAGGTG
3' ss Score
10.92
5' ss Seq
GAAGTAAGG
5' ss Score
6.38
Exon sequences
Seq C1 exon
CTCTAAGGTATTTCTGGAAATCGACAACCGACAGTGTGTTCAAGACTCAGACCAGTGCTTCAAGAACACAGATGCTGCAGCTGCTCTCCTGGCTTCTCATGCCATCCAAGGGACCTTGTCCTACCCTCTGGTGTCTGTTGTCA
Seq A exon
GTGAATCGGAGGATCCAAGGAACACTCCGCTCCTCTATCTGCTTGCGGTTGCTGTGGTCATTATCCTGTTCCTCATCCTGCTGGGGGTCATCATGGCAAAGCGGAAGCGCAAGCACGGCTTCCTCTGGCTGCCTGAAGGCTTCACGCTTCGCCGAGACTCCAGCAATCACAAGCGCCGTGAACCTGTGGGGCAGGATGCCGTGGGGCTGAA
Seq C2 exon
GAATCTCTCAGTGCAAGTGTCAGAGGCAAACCTGATCGGCTCCACGACAAGCGAGCATTGGGGTGATGATGAAGGACCCCAGCCAAAGAAAGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000018835-'43-36,'43-35,44-36=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.183 C2=0.576
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(78.7=100)
A:
PF076847=NODP=PD(14.8=12.7)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGTATTTCTGGAAATCGACAACC
R:
CTTGGCTTTCTTTGGCTGGGG
Band lengths:
236-447
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002958; ELM sequence: LWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]