MmuEX1018707 @ mm10
Exon Skipping
Gene
ENSMUSG00000027878 | Notch2
Description
notch 2 [Source:MGI Symbol;Acc:MGI:97364]
Coordinates
chr3:98138386-98139682:+
Coord C1 exon
chr3:98138386-98138528
Coord A exon
chr3:98138642-98138852
Coord C2 exon
chr3:98139586-98139682
Length
211 bp
Sequences
Splice sites
3' ss Seq
CCCTATGTCTGAACTCTCAGGTG
3' ss Score
7.96
5' ss Seq
GAAGTAAGA
5' ss Score
6.42
Exon sequences
Seq C1 exon
CTCTAAGATATTTCTGGAGATCGACAACCGACAGTGTGTTCAAGATTCAGACCAGTGCTTCAAAAACACAGATGCGGCAGCTGCTCTCCTGGCTTCTCATGCCATCCAAGGGACCCTATCCTACCCTCTAGTGTCTGTTTTCA
Seq A exon
GTGAACTGGAGAGTCCAAGAAACGCCCAGCTTCTCTATCTGCTCGCGGTCGCTGTTGTCATCATCCTGTTCTTCATCCTGCTGGGGGTCATCATGGCCAAGCGGAAGCGCAAGCATGGCTTCCTCTGGCTGCCGGAAGGGTTCACCCTCCGCCGAGACTCTAGCAATCACAAGCGCCGTGAACCTGTGGGACAGGATGCCGTGGGGCTGAA
Seq C2 exon
AAATCTCTCCGTGCAAGTGTCAGAGGCTAACCTGATTGGTTCTGGGACAAGTGAACATTGGGTTGATGATGAAGGACCCCAGCCAAAGAAAGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027878-'53-53,'53-52,54-53
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.155 C2=0.515
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(78.7=100)
A:
PF076847=NODP=PD(14.8=12.7)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGATATTTCTGGAGATCGACAACCG
R:
CTTGGCTTTCTTTGGCTGGGG
Band lengths:
236-447
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002958; ELM sequence: LWLP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types