DreEX0051147 @ danRer10
Exon Skipping
Gene
ENSDARG00000052139 | notch3
Description
notch 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]
Coordinates
chr3:53278426-53279080:-
Coord C1 exon
chr3:53278932-53279080
Coord A exon
chr3:53278611-53278839
Coord C2 exon
chr3:53278426-53278516
Length
229 bp
Sequences
Splice sites
3' ss Seq
AATTACCAATCCTTTTTTAGGTG
3' ss Score
9.98
5' ss Seq
GAAGTGAGT
5' ss Score
7.97
Exon sequences
Seq C1 exon
GTCCATTGTATATTTGGAAATAGACAACAGGCTGTGCTCTCAGGGCTCAGATGACTGCTTCCGCAATGCTGACAGTGCTGCTGAATACCTTGGTGCTCTGTCTGCTCGGGAGATGTTGCGCTTCCCATACCCCATTAAAGAAGTGACAA
Seq A exon
GTGAAAAAAGAGAGCCCTCGATTACTGAGATACCCGAATGGGCTAGGCTACTGCTAGTAGGTGTAGCTTCTCTCTTCTTGTTAGTAATCTTGATGGTTGGCATGTTGATTGCCCGCCGCAAGCGTGAACACAGCACACTCTGGTTCCCTGAGGGCTTCTTCCTCAAAAAGGAAACAAGCAGTAACAAGAACCGCAGAGAACCTGTGGGCCAAGATTCACTGGGCATGAA
Seq C2 exon
ACACATGCCAAAGACAGTGGAAGAGTCTCTTCTGGCTGATCACAGTGACCAGTGGATAGATACAGACTGCCCAGAGGCTAAGCGACTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000052139_MULTIEX1-15/19=14-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.247 C2=0.258
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(79.4=100)
A:
PF076847=NODP=PD(14.3=11.7)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTGGAAATAGACAACAGGCTGTG
R:
CTTAAGTCGCTTAGCCTCTGGG
Band lengths:
228-457
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002959; ELM sequence: LWFP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]