MmuEX0032055 @ mm9
Exon Skipping
Gene
ENSMUSG00000038146 | Notch3
Description
Notch gene homolog 3 (Drosophila) [Source:MGI Symbol;Acc:MGI:99460]
Coordinates
chr17:32274761-32276744:-
Coord C1 exon
chr17:32276590-32276744
Coord A exon
chr17:32276076-32276298
Coord C2 exon
chr17:32274761-32274845
Length
223 bp
Sequences
Splice sites
3' ss Seq
CTGCTGCTTCCATCCTACAGGAG
3' ss Score
9.83
5' ss Seq
GAAGTAAGA
5' ss Score
6.42
Exon sequences
Seq C1 exon
CTCTGTGGTGATGCTGGAGATTGACAACCGGCTCTGTCTGCAGTCAGCTGAGAATGACCACTGCTTCCCTGATGCCCAGAGTGCTGCTGACTACCTGGGAGCCTTGTCAGCAGTGGAGCGACTTGATTTCCCATACCCACTTCGGGATGTGCGAG
Seq A exon
GAGAGCCGCTGGAGGCCCCAGAGCAGAGCGTGCCACTGCTGCCACTGCTGGTGGCAGGGGCTGTCTTTCTACTCATCATCTTCATCCTGGGTGTCATGGTTGCCAGGCGAAAGCGAGAACACAGCACCCTCTGGTTCCCTGAGGGTTTTGCATTACACAAGGACATAGCTGCTGGCCACAAGGGCCGGAGGGAGCCTGTGGGACAAGATGCACTGGGAATGAA
Seq C2 exon
GAACATGGCCAAGGGTGAGAGTCTGATGGGGGAGGTGGTCACAGACTTGAATGACTCAGAATGTCCAGAGGCCAAGAGACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000038146-'30-34,'30-33,31-34
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.200 C2=0.552
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(80.0=100)
A:
PF076847=NODP=PD(13.8=12.0)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTGTGGTGATGCTGGAGAT
R:
TCAGTCTCTTGGCCTCTGGAC
Band lengths:
238-461
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002959; ELM sequence: LWFP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: