RnoEX0060478 @ rn6
Exon Skipping
Gene
ENSRNOG00000004346 | Notch3
Description
notch 3 [Source:RGD Symbol;Acc:620761]
Coordinates
chr7:14158120-14160105:-
Coord C1 exon
chr7:14159951-14160105
Coord A exon
chr7:14159438-14159660
Coord C2 exon
chr7:14158120-14158204
Length
223 bp
Sequences
Splice sites
3' ss Seq
CGGCTGCTTTTATCCTGCAGGAG
3' ss Score
10.22
5' ss Seq
GAAGTAAGA
5' ss Score
6.42
Exon sequences
Seq C1 exon
CTCTGTAGTGATGCTGGAGATTGACAACCGGCTCTGTCTGAAGTCAGCGGAGAACGACCACTGCTTCCCTGACGCCCAGAGTGCTGCCGACTACCTGGGAGCCTTGTCGGCAGTGGAGCGGCTTGATTTCCCATACCCACTACGGGATGTGCGAG
Seq A exon
GAGAGCCCTTGGAGCCTCCAGAGCAGAGCGTGCCACTGCTGCCGCTGCTGGTGGCAGGGGCTGTCTTTCTGCTGGTCATCTTCGTCCTGGGTGTCATGGTTGCCAGGCGCAAGCGAGAGCACAGCACCCTCTGGTTTCCTGAGGGTTTTGCATTACACAAGGACATAGCTGCTGGCCACAAGGGCCGGAGGGAGCCCGTGGGACAAGACGCACTGGGCATGAA
Seq C2 exon
GAACATGACCAAGGGTGAGAGTCTGATGGGGGAGGTGGCCACAGACTGGAATGACTCAGAATGCCCAGAGGCCAAGAGACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000004346-'31-31,'31-30,32-31
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.240 C2=0.793
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(80.0=100)
A:
PF076847=NODP=PD(13.8=12.0)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTAGTGATGCTGGAGATTGACA
R:
TTCAGTCTCTTGGCCTCTGGG
Band lengths:
236-459
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002959; ELM sequence: LWFP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]