GgaEX6015413 @ galGal4
Exon Skipping
Gene
ENSGALG00000002375 | NOTCH1
Description
notch 1 [Source:HGNC Symbol;Acc:HGNC:7881]
Coordinates
chr17:7837083-7838483:+
Coord C1 exon
chr17:7837083-7837231
Coord A exon
chr17:7837831-7838047
Coord C2 exon
chr17:7838393-7838483
Length
217 bp
Sequences
Splice sites
3' ss Seq
TGTGCCCCACTGCTTTCCAGGTG
3' ss Score
9.37
5' ss Seq
GAAGTGAGT
5' ss Score
7.97
Exon sequences
Seq C1 exon
ATCCATCGTCTACTTGGAAATTGACAACAGGCAGTGCATCCAGTCGTCCTCCCAGTGCTTCCAGAGCGCAACCGATGTGGCGGCCTTCCTGGGGGCCTTGGCCTCCCTGGGCAACCTCAACATTCCCTACAAAATAGAGGCCGTCAAGA
Seq A exon
GTGAAACGGCGGAGCCCGCGAGGAACTCCCAGCTGTATCCTATGTATGTGGTGGTGGCTGCACTGGTCTTGCTTGCCTTCATTGGAGTGGGAGTGCTGGTGTCCCGCAAGCGGCGCAGGGAGCATGGCCAGCTCTGGTTCCCAGAGGGCTTCAAAGTGACGGAGTCGAGCAAGAAGAAGCGCCGGGAACCACTTGGGGAAGATTCTGTTGGACTGAA
Seq C2 exon
ACCCCTCAAAAATGCTTCTGACGGCACGCTGATGGACGACAACCAAAATGAGTGGGGTGACGAGGAGACCCTGGACACCAAGAAGTTCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000002375-'30-33,'30-32,31-33=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.233 C2=0.903
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(79.4=100)
A:
PF076847=NODP=PD(14.3=12.3)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATCGTCTACTTGGAAATTGACA
R:
TGAACTTCTTGGTGTCCAGGG
Band lengths:
237-454
Functional annotations
There are 2 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002957; ELM sequence: LWFP; Overlap: FULL
PMID: 20028974
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, inferred by author, isothermal titration calorimetry, x-ray crystallography. ELM ID: ELMI002957; ELM sequence: LWFP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]