BtaEX6047249 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000022799 | NOTCH1
Description
Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:F1MSM3]
Coordinates
chr11:103992057-103993431:-
Coord C1 exon
chr11:103993283-103993431
Coord A exon
chr11:103992326-103992542
Coord C2 exon
chr11:103992057-103992144
Length
217 bp
Sequences
Splice sites
3' ss Seq
CGCGGCCGCTGTGCCCGCAGGTG
3' ss Score
11.23
5' ss Seq
CAAGTCAGT
5' ss Score
2.74
Exon sequences
Seq C1 exon
GTCCATCGTCTACCTGGAGATCGACAACCGGCAGTGCGTCCAGTCATCCTCCCAGTGCTTCCAGAGCGCCACGGACGTGGCCGCCTTCTTGGGCGCGCTGGCCTCGCTGGGCAGCCTTAACATCCCCTACAAGATCGAGGCTGTGCAGA
Seq A exon
GTGAGACGGTGGAGCCGCCCCCGCCGCCGCCGCTGCACTTCATGTATGTGGCTGTGGTGGCCTTCGTGTTGCTGTTCTTCGTGGGCTGCGGGGTGCTGCTGTCGCGGAAGCGCCGGCGGCAGCATGGCCAGCTCTGGTTCCCTGAGGGCTTCAAGGTGTCGGAGGCCAGCAAGAAGAAGCGGCGCGAGCCCCTCGGCGAGGACTCCGTGGGCCTCAA
Seq C2 exon
GCCCCTGAAGAACTCCTCGGACGGCGCCCTCATGGACGACAACCAGAACGAGTGGGGCGACGAGGGCCTGGAGGCCAAGAAGTTCCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000022799-'35-29,'35-28,36-29=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.039 A=0.288 C2=0.767
Domain overlap (PFAM):
C1:
PF076847=NODP=PU(83.3=98.0)
A:
PF076847=NODP=PD(15.0=12.3)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATCGTCTACCTGGAGATCG
R:
CCGGAACTTCTTGGCCTCCAG
Band lengths:
236-453
Functional annotations
There are 2 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002957; ELM sequence: LWFP; Overlap: FULL
PMID: 20028974
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, inferred by author, isothermal titration calorimetry, x-ray crystallography. ELM ID: ELMI002957; ELM sequence: LWFP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]