MmuEX0032055 @ mm10
Exon Skipping
Gene
ENSMUSG00000038146 | Notch3
Description
notch 3 [Source:MGI Symbol;Acc:MGI:99460]
Coordinates
chr17:32137816-32139799:-
Coord C1 exon
chr17:32139645-32139799
Coord A exon
chr17:32139131-32139353
Coord C2 exon
chr17:32137816-32137900
Length
223 bp
Sequences
Splice sites
3' ss Seq
CTGCTGCTTCCATCCTACAGGAG
3' ss Score
9.83
5' ss Seq
GAAGTAAGA
5' ss Score
6.42
Exon sequences
Seq C1 exon
CTCTGTGGTGATGCTGGAGATTGACAACCGGCTCTGTCTGCAGTCAGCTGAGAATGACCACTGCTTCCCTGATGCCCAGAGTGCTGCTGACTACCTGGGAGCCTTGTCAGCAGTGGAGCGACTTGATTTCCCATACCCACTTCGGGATGTGCGAG
Seq A exon
GAGAGCCGCTGGAGGCCCCAGAGCAGAGCGTGCCACTGCTGCCACTGCTGGTGGCAGGGGCTGTCTTTCTACTCATCATCTTCATCCTGGGTGTCATGGTTGCCAGGCGAAAGCGAGAACACAGCACCCTCTGGTTCCCTGAGGGTTTTGCATTACACAAGGACATAGCTGCTGGCCACAAGGGCCGGAGGGAGCCTGTGGGACAAGATGCACTGGGAATGAA
Seq C2 exon
GAACATGGCCAAGGGTGAGAGTCTGATGGGGGAGGTGGTCACAGACTTGAATGACTCAGAATGTCCAGAGGCCAAGAGACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000038146-'41-47,'41-45,42-47
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.200 C2=0.552
Domain overlap (PFAM):
C1:
PF076847=NODP=FE(80.0=100)
A:
PF076847=NODP=PD(13.8=12.0)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTGTGGTGATGCTGGAGAT
R:
TCAGTCTCTTGGCCTCTGGAC
Band lengths:
238-461
Functional annotations
There are 1 annotated functions for this event
PMID: 16530045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: inferred by author. ELM ID: ELMI002959; ELM sequence: LWFP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types