DmeEX0000841 @ dm6
Exon Skipping
Gene
FBgn0033368 | CG13743
Description
This gene is referred to in FlyBase by the symbol DmelCG13743 (FBgn0033368). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:9044850..9060608. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:9056573-9059548:-
Coord C1 exon
chr2R:9059255-9059548
Coord A exon
chr2R:9058974-9059143
Coord C2 exon
chr2R:9056573-9056632
Length
170 bp
Sequences
Splice sites
3' ss Seq
ACTCGAGCACTTCCTTGCAGCAC
3' ss Score
4.24
5' ss Seq
CAGGTTTCT
5' ss Score
-0.33
Exon sequences
Seq C1 exon
GCGGATGCTGGTACACATATTTATTCAGCTACTGCTTATGGCCAGCCAACTACCCACCTAAACTAAACCGAAACCAGAGCTAAAACTAAACTGAAAACGAAATCAAAACCAAAACTAACTAAACGAACTGAACTATAAAGAAGCCAGTGGCTGTTACAACTTTCACTACTAGCAAAGTTGGACCAAAGGCAAAAGGCAAAAGCAGAAGCAACCCGACCAAGCAACATGAACATGAACATGAACGACAGTCGACGCAACACCGCCACGGAATTCAGCTATATCCTGCAGCGCCAG
Seq A exon
CACCCTAATTGCACACTTCCCAGCCGCAGGAACTCCGACTAATTGCAGCCACACGAACTGACTGATTGGCCAGCTGCCCACTGAGTGCATAATGACCGGGATTGTGGCAGAAGTCGGGGTTCTCAGCGGTGCCCAGTTGTTCCATTCGGAACAACTTCCACTTTCACCAG
Seq C2 exon
GGCAGCGATGTGTCGGTTGCCGAGGCTTATGCATTCGATGACTTCAACAATATAATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033368_MULTIEX2-1/4=C1-2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.978 A=1.000 C2=0.200
Domain overlap (PFAM):
C1:
PF046958=Pex14_N=PU(16.5=82.6)
A:
NO
C2:
PF046958=Pex14_N=FE(15.8=100)
Main Inclusion Isoform:
FBtr0088662fB120
Main Skipping Isoform:
FBpp0087743
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGAGCTAAAACTAAACTGAAAACG
R:
AATGCATAAGCCTCGGCAACC
Band lengths:
256-426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)