DmeEX0000844 @ dm6
Exon Skipping
Gene
FBgn0033368 | CG13743
Description
This gene is referred to in FlyBase by the symbol DmelCG13743 (FBgn0033368). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:9044850..9060608. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:9049880-9059548:-
Coord C1 exon
chr2R:9059255-9059548
Coord A exon
chr2R:9050515-9050629
Coord C2 exon
chr2R:9049880-9050132
Length
115 bp
Sequences
Splice sites
3' ss Seq
AAGCCTCATTTCATTTGCAGGTC
3' ss Score
9.01
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
GCGGATGCTGGTACACATATTTATTCAGCTACTGCTTATGGCCAGCCAACTACCCACCTAAACTAAACCGAAACCAGAGCTAAAACTAAACTGAAAACGAAATCAAAACCAAAACTAACTAAACGAACTGAACTATAAAGAAGCCAGTGGCTGTTACAACTTTCACTACTAGCAAAGTTGGACCAAAGGCAAAAGGCAAAAGCAGAAGCAACCCGACCAAGCAACATGAACATGAACATGAACGACAGTCGACGCAACACCGCCACGGAATTCAGCTATATCCTGCAGCGCCAG
Seq A exon
GTCAGATGCGGCCACATCTGCGGTCGGTTCAGCTATCCGGGCATCATGGAGGCGGCCTACGGCAAGTACGGCTATTACCTGCTCTCCCTGCTGCAGTTCATGTATCCATTCCTGG
Seq C2 exon
CCATGATTTCCTACAACGTGGTGGTGGGCGATACGCTGTCGAAGGTTCTGGTCCGCTTCTTCCCCTCCTGGGGCGGTTCCATGGGCGCCGTCCGACTGGGCGTGGTCTTCTTCGTCAACGTGGGCGTGGTGATGCCCCTCTGTCTCTACAAGAACGTCTCCAGACTGGCCAGAGCCAGCTTCATTAGCCTGGCGTGCGTGGTCTTCATCCTGTTTGCCGTCATCATCAAGCTCATGTCGGGCGATTATAAGGT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033368_MULTIEX2-4/4=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.978 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF046958=Pex14_N=PU(16.5=82.6)
A:
PF0149013=Aa_trans=FE(21.0=100)
C2:
PF0149013=Aa_trans=FE(20.6=100)
Main Inclusion Isoform:
FBpp0087743
Main Skipping Isoform:
FBtr0088662fB120
Other Inclusion Isoforms:
FBpp0300980, FBpp0308396
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCAAAGTTGGACCAAAGGCA
R:
ACGTTGACGAAGAAGACCACG
Band lengths:
245-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)