DmeEX0000842 @ dm6
Exon Skipping
Gene
FBgn0033368 | CG13743
Description
This gene is referred to in FlyBase by the symbol DmelCG13743 (FBgn0033368). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:9044850..9060608. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr2R:9050843-9059548:-
Coord C1 exon
chr2R:9059255-9059548
Coord A exon
chr2R:9056573-9056632
Coord C2 exon
chr2R:9050843-9051151
Length
60 bp
Sequences
Splice sites
3' ss Seq
ATTTTCATGCGATCCACCAGGGC
3' ss Score
6.25
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
Exon sequences
Seq C1 exon
GCGGATGCTGGTACACATATTTATTCAGCTACTGCTTATGGCCAGCCAACTACCCACCTAAACTAAACCGAAACCAGAGCTAAAACTAAACTGAAAACGAAATCAAAACCAAAACTAACTAAACGAACTGAACTATAAAGAAGCCAGTGGCTGTTACAACTTTCACTACTAGCAAAGTTGGACCAAAGGCAAAAGGCAAAAGCAGAAGCAACCCGACCAAGCAACATGAACATGAACATGAACGACAGTCGACGCAACACCGCCACGGAATTCAGCTATATCCTGCAGCGCCAG
Seq A exon
GGCAGCGATGTGTCGGTTGCCGAGGCTTATGCATTCGATGACTTCAACAATATAATGAAG
Seq C2 exon
AACAACCATCAGACACATCAGCAACAGGGCCAGCCGCAACAGCCACATCAGCAGCAGCAGCAGCCGCCGCAGCAGCAGCAGCAGCAACAGCATCGCCAGCATTCGCAGCAGCAGCAGCAAGCACAGCAGGATGCCGGACTGGGGGACACGCTGTCCTCGCTGCCACAGGCCTCGTTCAACTACATCAACTCCATCGTGGGCAGCGGCGTCATCGGCATACCCTACGCCCTTCACAGGGCCGGATTCGGACTGGGCCTGGCCCTGCTCATCCTGGTGGCCTACATCACCGACTACTCACTCATCCTGATG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0033368_MULTIEX2-2/4=C1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.978 A=0.200 C2=0.466
Domain overlap (PFAM):
C1:
PF046958=Pex14_N=PU(16.5=82.6)
A:
PF046958=Pex14_N=FE(15.8=100)
C2:
PF046958=Pex14_N=PD(72.5=84.5),PF0149013=Aa_trans=PU(13.0=51.5)
Main Inclusion Isoform:
FBpp0087743
Main Skipping Isoform:
FBpp0300980
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
FBpp0308396
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTGGACCAAAGGCAAAAGGC
R:
CCCTGTTGCTGATGTGTCTGA
Band lengths:
147-207
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)