DreEX0000008 @ danRer10
Exon Skipping
Gene
ENSDARG00000078183 | A2ML1 (10 of 13)
Description
alpha-2-macroglobulin-like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr3:3678410-3679327:+
Coord C1 exon
chr3:3678410-3678531
Coord A exon
chr3:3678614-3678839
Coord C2 exon
chr3:3679207-3679327
Length
226 bp
Sequences
Splice sites
3' ss Seq
GGTGTGTGTGTTTATTTCAGAGA
3' ss Score
8.44
5' ss Seq
AAGGTCTGG
5' ss Score
3.93
Exon sequences
Seq C1 exon
GTTCTAAATGCTCCTGTACCTGTAGAACTAGGAGAACTTGTTAGAGGTGACAGTGGTTCCTCTGCTGTGACCATCAGGACTTACTTTCCAGAAACCTGGATTTGGCAACTTGTTACTGTGGG
Seq A exon
AGACTCTGGGTCCACGTCAGTTCCCCTCACAGTTCCTGACACAATCACTGCATGGGACACCGAGGCCTTCTGTCTAGCCTCCAGTGGTTTTGGTCTGGCTCCACCAGTTCTGCTGACTTCCTTCCAGCCCTTCTTTCTGGAGATCACCCTGCCTTACTCCATAATCCGTGGGGAGATTTTAAATCTGAAGGCCACTGTCTTTAATTATCTGCCCCAATGCATCAAG
Seq C2 exon
GTTCAAGTGACTCCAACACCATCCTCCAACTTCACTCTTAAATCCTTTGGTCACTATTCATCCCATCTCTCTGCCAATGGGAGAAAGACCTTCAAATGGGATTTAACTGCTTCTGTTATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000078183-'22-27,'22-25,23-27
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0020717=A2M=PU(10.0=22.0)
A:
PF0020717=A2M=FE(83.3=100)
C2:
PF0020717=A2M=PD(4.4=9.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCTAAATGCTCCTGTACCTGT
R:
ACAGAAGCAGTTAAATCCCATTTGA
Band lengths:
238-464
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]