DreEX0005897 @ danRer10
Exon Skipping
Gene
ENSDARG00000074808 | MEGF6 (1 of 2)
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr11:41112631-41117816:-
Coord C1 exon
chr11:41117688-41117816
Coord A exon
chr11:41117148-41117276
Coord C2 exon
chr11:41112631-41112762
Length
129 bp
Sequences
Splice sites
3' ss Seq
TGTGTGTGTGTGTGTTGTAGCAT
3' ss Score
10.23
5' ss Seq
ACAGTATGT
5' ss Score
6.05
Exon sequences
Seq C1 exon
AGTGTGAACGGGGCTGGTTTGGCGTGGGTTGTGAGGACCGCTGTCAGTGTGATCACGGTGCTGTCTGCCATCACGTGAGCGGTCAGTGTCTCTGCCCTGCTGGATGGAGAGGAAGACGCTGTGAGAAAG
Seq A exon
CATGTCTGCCGGGCTCATTTGGTCAGGATTGTGTCCAGCGCTGCTCTTGTCCGTCCGGCTCCTCGTGTCATCATGTGACCGGTCACTGTGGTTGTGCTCCAGGATTCACCGGCGACGGCTGTGAACACA
Seq C2 exon
GTTGTCTGCCTGGCACGTTCGGCCAGGACTGTAATCAGGTGTGTCAGTGTTCAGAAAGAAACCAGCTCTGCCACCCGGTGACTGGAGTGTGTTACTGCGCGCCCGGATTCACTGGACTCAAGTGTGAACAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074808_MULTIEX1-7/7=6-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(63.0=65.9)
A:
PF0005319=Laminin_EGF=PD(34.8=36.4)
C2:
PF0005319=Laminin_EGF=PU(63.8=66.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTGAACGGGGCTGGTTTG
R:
CTTGAGTCCAGTGAATCCGGG
Band lengths:
250-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]