HsaEX6027940 @ hg38
Exon Skipping
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3496655-3498499:-
Coord C1 exon
chr1:3498371-3498499
Coord A exon
chr1:3497233-3497361
Coord C2 exon
chr1:3496655-3496783
Length
129 bp
Sequences
Splice sites
3' ss Seq
CAGCCCTCATCTTTCTGCAGCCT
3' ss Score
6.58
5' ss Seq
AGGGTAGGT
5' ss Score
8.1
Exon sequences
Seq C1 exon
AGTGCCTCCCCCGGGACGTCAGAGCTGGCTGCCGGCACAGCGGCGGTTGCCTCAACGGGGGCCTGTGTGACCCGCACACGGGCCGCTGCCTCTGCCCAGCCGGCTGGACTGGGGACAAGTGTCAGAGCC
Seq A exon
CCTGCCTGCGGGGCTGGTTTGGAGAGGCCTGTGCCCAGCGCTGCAGCTGCCCGCCTGGCGCTGCCTGCCACCACGTCACTGGGGCCTGCCGCTGTCCCCCTGGCTTCACTGGCTCCGGCTGCGAGCAGG
Seq C2 exon
GATGTCCGCCCGGGCGGTATGGGCCAGGCTGTGAACAGCTGTGTGGGTGTCTCAACGGGGGCTCCTGTGATGCGGCCACGGGGGCCTGCCGCTGCCCCACTGGGTTCCTCGGGACGGACTGCAACCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-'62-66,'62-64,66-66
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.051 C2=0.236
Domain overlap (PFAM):
C1:
PF079748=EGF_2=WD(100=70.5)
A:
PF0005319=Laminin_EGF=PU(67.4=65.9)
C2:
PF0005319=Laminin_EGF=PD(34.0=36.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGTCAGAGCTGGCTGC
R:
TGAGGTTGCAGTCCGTCCC
Band lengths:
244-373
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains