DreEX0011253 @ danRer10
Exon Skipping
Gene
ENSDARG00000076270 | adamts13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:ZFIN;Acc:ZDB-GENE-070814-7]
Coordinates
chr8:45239603-45249108:-
Coord C1 exon
chr8:45248961-45249108
Coord A exon
chr8:45243898-45244027
Coord C2 exon
chr8:45239603-45239798
Length
130 bp
Sequences
Splice sites
3' ss Seq
GATTGCTCTTTATGTTGTAGGCA
3' ss Score
9.09
5' ss Seq
CAGGTGACT
5' ss Score
6.6
Exon sequences
Seq C1 exon
GTGTATCGGAAATATGGACAAGAGTATGGAGACCTCACCAATCCAAATATCTCATACCAGTACTACTCAGATGATGTTATAGTGGAAATAGCTTCAAAGGGCAAATGGTCCACTACCATATCTGCCTGCTCAGTGACCTGTGGAAGAG
Seq A exon
GCATCCAGAAAATTTATCAACACTGTGTGGATCTGGTCACACTTGAACACCTGAAAGATGAGCTCTGCAGTTCACTACCTCGGTCGTCTGACCTGCTGCAGCCCTGCTTCCTGCCAGATTGCCCACCCAG
Seq C2 exon
ATGGCAGGTCTCTGAGCCTGGTGAGTGCTCCACTGTATGTGGTCCCGGGGAGGCCCAAAGAAAAGTCTTCTGTGTCCGCTTCCATAATAAATCTTATTTGGAGGTTGACCAAAACCTGTGCTCTCAACCCAAACCCCCAGAATACGTTCCCTGTGTGGTGGATGTTTGCCCTCTCAAATGGGACACTGAAAATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000076270-'17-20,'17-19,18-20
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF059869=ADAM_spacer1=PD(19.4=48.0),PF0009014=TSP_1=PU(26.3=30.0)
A:
PF0009014=TSP_1=PD(71.9=93.2)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTCAAAGGGCAAATGGTCC
R:
CAGTGTCCCATTTGAGAGGGC
Band lengths:
246-376
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]