DreEX0024854 @ danRer10
Exon Skipping
Gene
ENSDARG00000023472 | ctnnb2
Description
catenin, beta 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2575]
Coordinates
chr19:48333885-48336028:-
Coord C1 exon
chr19:48335775-48336028
Coord A exon
chr19:48334329-48334567
Coord C2 exon
chr19:48333885-48334045
Length
239 bp
Sequences
Splice sites
3' ss Seq
CATCTCTCCTGCTCCTCCAGGTG
3' ss Score
11.24
5' ss Seq
CGGGTGAGA
5' ss Score
7.62
Exon sequences
Seq C1 exon
ATCTGGACGGGCAGTATGCCATGACGCGGGCGCAGAGGGTTCGAGCCGCCATGTTCCCAGAGACTCTGGATGAGAGCGTCCCGATGGCCTCCACCCAGTTCGACTCTGCTCATCCAACAAACGTACAGCGTCTGGCGGAGCCGTCGCAGATGCTGAAGCATGCGGTGGTCAACCTCATCAACTACCAGGACGATGCAGAGCTCGCCACCAGAGCCATTCCAGAGCTCACCAAACTGCTGAACGACGAGGACCAG
Seq A exon
GTGGTGGTGAATAAAGCCGCAGTGATGGTGCACCAGCTCTCCAAGAAGGAGGCGTCCCGCCATGCCATCATGCGCTCTCCACAGATGGTGTCGGCCATCGTGAGGACCATGCAGAACACCAACGATGTGGAGACGGCCCGCTGCACCGCCGGCACACTGCACAACCTGTCCCACCACAGAGAGGGGCTGCTGGCCATCTTCAAGAGCGGAGGGATCCCGGCCCTCGTCAAGATGCTCGG
Seq C2 exon
GTCTCCTGTGGACAGTGTGCTGTTTTACGCCATCACCACCCTCCACAACCTCCTGCTGCATCAGGAAGGGGCCAAGATGGCTGTGCGTCTGGCTGGAGGTCTGCAGAAGATGGTGGCGCTGCTCAACAAAACCAACGTCAAGTTCCTCGCCATCACCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000023472-'8-7,'8-6,9-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.412 A=0.075 C2=0.000
Domain overlap (PFAM):
C1:
PF136461=HEAT_2=PU(46.1=55.3)
A:
PF136461=HEAT_2=PD(52.0=66.2),PF0051418=Arm=PU(51.2=26.2)
C2:
PF0051418=Arm=PD(46.3=34.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCCAGTTCGACTCTGCTCAT
R:
CGTTGGTTTTGTTGAGCAGCG
Band lengths:
299-538
Functional annotations
There are 1 annotated functions for this event
PMID: 11533658
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, glutathione s tranferase tag, phosphatase assay, pull down. ELM ID: ELMI001964; ELM sequence: MLGSPV; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]