DreEX0051145 @ danRer10
Exon Skipping
Gene
ENSDARG00000052139 | notch3
Description
notch 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]
Coordinates
chr3:53276902-53280175:-
Coord C1 exon
chr3:53279646-53280175
Coord A exon
chr3:53279240-53279563
Coord C2 exon
chr3:53276902-53276999
Length
324 bp
Sequences
Splice sites
3' ss Seq
TACACTTTCTCTTCCCTCAGCCC
3' ss Score
8.93
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
ATGAACTGCAAAGAGCTGCCTTGCTACAATGGAGGCAGTTGCACTCTCACCACACGAGGGGCACGTTGTACTTGCATTCAGGGCTTTGGTGGGCCATTGTGTCAGCACCGCAGCAATGACGGCTGCTCCTCCAAGCCATGCCACAATGGAGGCTTATGTACAGAGGAAACCAGCTATCCATTTTTTCACTGCCAGTGCACCAATGGCTGGAAAGGCAAACGATGTGAACAGAAAACTGGGTCATCGGCTCCACTTCCTTCTCCTTGCCCTATTGCTGACTGCTTCAGCAAGGCCAATGACGGTGTGTGTGACAAAGAATGCAACTCCTTAGACTGCCGCTGGGACGGAGGTGACTGTTCTCTTGCTGTAAACCCCTGGGCACGCTGTGCAGACCCTCGATGCTGGCGGCTCTTCAATAACAGCCAATGTGACGAGTTTTGCAATAACGCAGAGTGCCTGTTCGATAATTTCGACTGCATAAACAAAGAGAAAGTCTGCAA
Seq A exon
CCCCATCTATGAAGCATACTGCACTGACCATTATGCAGATGGACTCTGTGATCAAGGATGCAATACTGAAGAATGTGGCTGGGATGGACTGGATTGTGCAAGGAAGATTCCAGAAGACCTTGCTGAAGATATGCTTGTTATTGTAGTCCTACTGCCCCCAGAGGAGCTTCTAAGGACACAAACAGCTTTCCTGCAGAAACTAAGTGCCATCCTACGCACCACGTTGCGCTTCCGTCTCGATCGAAATGGAGATTACATGATCCGACCTTACACAGGCCGTGAGACGCGCATTAAACGGGAGCTTAATCCTCAGGAGGTCATTGG
Seq C2 exon
GAAAGTCAGCATTGCACTGGGCAGCAGCAGTCAATAACGTTGAAGCTACTATTGCCTTGTTGAAGAATGGTGCCAATAAAGATATGCAAGACCTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000052139_MULTIEX1-13/19=12-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.030
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(14.7=2.8),PF0000822=EGF=WD(100=17.5),PF0000822=EGF=WD(100=18.6),PF0006612=Notch=WD(100=20.3),PF0006612=Notch=WD(100=20.9),PF0006612=Notch=PU(15.0=3.4)
A:
PF0006612=Notch=PD(82.5=30.3),PF068168=NOD=WD(100=52.3),PF076847=NODP=PU(4.8=2.8)
C2:
PF127962=Ank_2=FE(34.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGAAAACTGGGTCATCGGC
R:
GGCACCATTCTTCAACAAGGC
Band lengths:
347-671
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]