DreEX0051461 @ danRer10
Exon Skipping
Gene
ENSDARG00000103176 | nr5a1a
Description
nuclear receptor subfamily 5, group A, member 1a [Source:ZFIN;Acc:ZDB-GENE-010504-1]
Coordinates
chr8:52860566-52870618:-
Coord C1 exon
chr8:52870477-52870618
Coord A exon
chr8:52864477-52864916
Coord C2 exon
chr8:52860566-52860724
Length
440 bp
Sequences
Splice sites
3' ss Seq
CTCTCTCTTTGTCTTCTCAGCTG
3' ss Score
9.78
5' ss Seq
CAGGTATGA
5' ss Score
9.46
Exon sequences
Seq C1 exon
GGTTTTTTCAAGAGGACAGTTCAGAATAACAAGAGATACACGTGCACACAGAACCAGGACTGCGGCATCGACAAAACTCAGAGGAAAAGATGTCCGTTCTGCCGCTTCCAGAAGTGTCTGAGTGTCGGCATGAGACTTGAGG
Seq A exon
CTGTGCGTGCAGACCGGATGAGAGGTGGAAGAAATAAGTTTGGCCCAATGTACAAGCGAGACCGAGCCTTAAAGCAGCAGAAGCGAGCTTTAATCCGAGCTAGCGGCTTCAAACTGGAGGCTAACGGGACGCTGCTGTCGGGACAGACAGAGTTCAGTTCTGTAGGTCTGCAGTCTCCCTATGACTGTCCTCCGCCTGCTCTCGGAGTCGCTCTGCAGAATTACGGCTCATTCCCAGCACAGTATCAGTACACGGCTCCGTCTCTACCCAAATCCATCAAAGCCGAGTATCCGGACGCGTACTCCAGCTCTCCGGACTCCACGCTGGGTTACTCATACGCTGATGGATGCCTGAGCGCTTCACCACACAGTGTCCCCATAAACCCTGCGCTGCCGCCGCTGGTGCTGGAGCTGCAGAGCTGCGACCCAGATGAGGAGCAG
Seq C2 exon
GTGAGAGGAAAGATCTGCGCGTATCTCCACCAGGAGCAGAGTGGCAGAGGAAAGCTGGAGAAATCGCGACCCTTCAGCCTGCTGTGTGTCATGGCCGACCAGACGCTCTTCTCTATCGTGGAGTGGGCGAGAAGCTGTGTCTTCTTCAAGGAACTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000103176-'5-5,'5-4,7-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.035 C2=0.000
Domain overlap (PFAM):
C1:
PF0010513=zf-C4=PD(64.3=93.8)
A:
NO
C2:
PF0010425=Hormone_recep=PU(23.0=86.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTTCAAGAGGACAGTTCAGAATAA
R:
AGTTCCTTGAAGAAGACACAGCT
Band lengths:
294-734
Functional annotations
There are 1 annotated functions for this event
PMID: 19995909
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, gal4 vp16 complementation, mutation analysis. ELM ID: ELMI002003; ELM sequence: PYASPP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]