DreEX6035349 @ danRer10
Exon Skipping
Gene
ENSDARG00000055934 | si:ch1073-416j23.1
Description
si:ch1073-416j23.1 [Source:ZFIN;Acc:ZDB-GENE-100922-35]
Coordinates
chr9:10828577-10829069:-
Coord C1 exon
chr9:10828933-10829069
Coord A exon
chr9:10828773-10828845
Coord C2 exon
chr9:10828577-10828633
Length
73 bp
Sequences
Splice sites
3' ss Seq
TTTCCTTGTCTTTCCATCAGGTT
3' ss Score
11.32
5' ss Seq
TTGGTGGAG
5' ss Score
-6.9
Exon sequences
Seq C1 exon
GAGCGGCAGATGCAGCTGATATGTGATGTACTGGTGCATGACAGCAAGTCAAATGCCTGTCTGAATGATGAGCAGAGGTCAATGCTGACCAGCTTCAGTCATAAAGGAGCCTGTGTCCCGCAACACAGAGGAAAACG
Seq A exon
GTTATCAGTGATAGATGAATCCTCCTTTCTGTCGCACTCTGACATTAGTTATGACAGAACGGATGATGATTTG
Seq C2 exon
GACTTGGACAGCACTGCGTTTGTCAAGCCTCTCAAGTCAAGAGCTCGTGAGAGAAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000055934-'2-3,'2-2,3-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.022 A=0.000 C2=0.158
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGCAGATGCAGCTGATATGT
R:
TGAGAGGCTTGACAAACGCAG
Band lengths:
168-241
Functional annotations
There are 2 annotated functions for this event
PMID: 19468300
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, mutation analysis, protein kinase assay. ELM ID: ELMI003372; ELM sequence: SDISFDK; Overlap: FULL
PMID: 27453045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, isothermal titration calorimetry. ELM ID: ELMI003173; ELM sequence: LSTIDE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]