DreEX6065225 @ danRer10
Exon Skipping
Gene
ENSDARG00000062686 | megf11
Description
multiple EGF-like-domains 11 [Source:ZFIN;Acc:ZDB-GENE-060503-252]
Coordinates
chr18:19256340-19333003:-
Coord C1 exon
chr18:19332911-19333003
Coord A exon
chr18:19259729-19259975
Coord C2 exon
chr18:19256340-19256460
Length
247 bp
Sequences
Splice sites
3' ss Seq
GTTTGTTCTCTGTTTTTCAGGTT
3' ss Score
11.95
5' ss Seq
CATGTGAGT
5' ss Score
7.83
Exon sequences
Seq C1 exon
CTCGATGTAGCGAGGAGTGTGCCCATGGTCGTTGTGTGTCTCCTGATACGTGTCAGTGTGAGCCAGGCTGGGGAGGACTGGACTGCTCTAGTG
Seq A exon
GTTGTGAAAGTGGCTACTGGGGCCCCCATTGCAGCAACCGTTGTCAGTGCAAGAATGGGGCCCTGTGTAACCCCATCACAGGGGCCTGTGTCTGCACAGACGGCTACCAAGGCTGGCGCTGTGAGGATCTGTGTGAGCCCGGCTACTATGGCAAGGGCTGCCAGCTGCAGTGTCAATGCCTCAACGGTGCCACCTGCCACCACGAGACGGGGGAATGCATATGCGCACCAGGCTACATGGGCCCCAT
Seq C2 exon
CTGTGGAGAGCGCTGTCCCTCTGGAAGTCACGGGCCACAGTGTGAGCAGCGATGCCCCTGTCAGAACGGAGGAACCTGCCATCACATCACTGGGGAGTGTTCCTGCCCGGCTGGATGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062686-'3-5,'3-4,4-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0005319=Laminin_EGF=WD(100=61.4),PF126612=hEGF=PU(84.6=13.3)
C2:
PF126612=hEGF=PD(7.7=2.4),PF126612=hEGF=PU(61.5=19.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGATGTAGCGAGGAGTGTGC
R:
GTCCATCCAGCCGGGCAG
Band lengths:
212-459
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]