RnoEX6036181 @ rn6
Exon Skipping
Gene
ENSRNOG00000010634 | Megf11
Description
multiple EGF-like-domains 11 [Source:RGD Symbol;Acc:1582797]
Coordinates
chr8:70016999-70114800:+
Coord C1 exon
chr8:70016999-70017091
Coord A exon
chr8:70112923-70113169
Coord C2 exon
chr8:70114680-70114800
Length
247 bp
Sequences
Splice sites
3' ss Seq
CAGCGTGTCCTTTCTTGCAGGCT
3' ss Score
9.32
5' ss Seq
TTAGTGAGT
5' ss Score
5.79
Exon sequences
Seq C1 exon
CTCTGTGCACCGAGGAGTGTATGCATGGCCGCTGCGTCTCCCCGGATACCTGCCACTGTGAGCCTGGATGGGGAGGCCCTGACTGTTCCAGTG
Seq A exon
GCTGTGACAGCGAGCACTGGGGTCCCCACTGCAGCAACCGGTGTCAGTGTCAGAACGGCGCCTTGTGCAACCCTATCACCGGCGCCTGCGTATGCGCCCCCGGCTTCCGAGGCTGGCGCTGTGAGGAATTCTGCGCGCCCGGTACTCACGGCAAGGGCTGCCAGCTGCTCTGTCAGTGCCACCACGGCGCTAGCTGCGACCCGCGCACTGGCGAGTGCCTCTGCGCACCAGGCTACACCGGCGTTTA
Seq C2 exon
CTGTGAGGAGCTGTGCCCCCCTGGGAGCCATGGAGCTCACTGTGAGCTACGCTGCCCCTGCCAGAACGGAGGCACCTGCCACCACATCACTGGCGAGTGTGCCTGTCCTCCAGGCTGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010634-'7-15,'7-12,13-15=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.052 C2=0.044
Domain overlap (PFAM):
C1:
PF079748=EGF_2=PD(68.3=87.5)
A:
PF0005319=Laminin_EGF=WD(100=54.2),PF0005319=Laminin_EGF=PU(54.3=30.1)
C2:
PF0005319=Laminin_EGF=PD(43.5=48.8),PF126612=hEGF=PU(61.5=19.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGTGCACCGAGGAGTGTAT
R:
CTGGAGGACAGGCACACTCG
Band lengths:
205-452
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]