HsaEX6075427 @ hg19
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66273116-66386832:-
Coord C1 exon
chr15:66386740-66386832
Coord A exon
chr15:66274580-66274826
Coord C2 exon
chr15:66273116-66273236
Length
247 bp
Sequences
Splice sites
3' ss Seq
GACTGTCCCGTCTCTTGCAGGCT
3' ss Score
10.89
5' ss Seq
CTAGTGAGT
5' ss Score
7.43
Exon sequences
Seq C1 exon
CCCTGTGTACGGAGGAGTGTGTGCACGGCCGCTGCGTTTCCCCGGACACCTGCCACTGCGAGCCTGGCTGGGGAGGGCCCGACTGCTCCAGCG
Seq A exon
GCTGCGACAGCGACCACTGGGGGCCCCACTGCAGCAACCGGTGCCAGTGCCAGAACGGCGCCCTGTGTAACCCCATCACAGGCGCCTGCGTGTGCGCCGCCGGCTTCCGTGGATGGCGCTGCGAGGAGCTCTGCGCACCTGGCACCCACGGCAAGGGATGCCAGCTGCCGTGCCAGTGCCGACACGGTGCCAGCTGCGACCCCCGCGCCGGCGAGTGCCTCTGCGCACCTGGCTACACCGGCGTCTA
Seq C2 exon
CTGCGAGGAGCTGTGCCCTCCTGGGAGCCATGGAGCTCACTGTGAGCTGCGCTGCCCCTGTCAGAATGGGGGCACCTGCCACCACATCACTGGCGAGTGTGCCTGCCCCCCAGGCTGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'4-6,'4-5,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079748=EGF_2=PD(82.4=87.5)
A:
PF0005319=Laminin_EGF=PU(56.8=30.1)
C2:
PF0005319=Laminin_EGF=PD(40.9=43.9),PF126612=hEGF=PU(61.5=19.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGTGTACGGAGGAGTGTGT
R:
CTCGCCAGTGATGTGGTGG
Band lengths:
189-436
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)