DreEX6076194 @ danRer10
Exon Skipping
Gene
ENSDARG00000013892 | sorl1
Description
sortilin-related receptor, L(DLR class) A repeats containing [Source:ZFIN;Acc:ZDB-GENE-050208-22]
Coordinates
chr15:21620439-21621720:-
Coord C1 exon
chr15:21621592-21621720
Coord A exon
chr15:21621346-21621472
Coord C2 exon
chr15:21620439-21620608
Length
127 bp
Sequences
Splice sites
3' ss Seq
CCTGATTTTGCATTTCCCAGATG
3' ss Score
7.69
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
Exon sequences
Seq C1 exon
CCACTCATGGCCCTCTGCTCTGTGCGAATGGTACGCGGTGTGCAGACGGCGAGGCCTGTTTGCTGAACAGCGAGAGGTGTGATGGTTTTATAGACTGCTCTGACCGAAGTGACGAGCACAACTGCACTG
Seq A exon
ATGAACAGCAGGTCTACAAGGTTCAGAATCTACAGTGGACTGCCAATTTCTCTGGAGCTGTCAAGCTTACATGGACAAGGCCTAAAAATATGCCTACATCCTCCTGTTCTTTTGTCATCTACTTCAG
Seq C2 exon
GCCAGTGGGTGTACAACAGTGGACGTCAATAGACACAAACAGCAATAAGGGTAGTGCCGTTCTGACCGTGTTGATGCCAGACACCACATACAACGTGAAGGTTCAGACTCAGTGCCTTAGCAAACAGCACAGGACCAATGAATATCTTACTCTGCGCACTCCAGAAGGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000013892-'37-42,'37-41,38-42=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.138
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=81.8)
A:
PF0004116=fn3=PU(46.8=86.0)
C2:
PF0004116=fn3=PD(51.9=70.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGCTCTGTGCGAATGGTAC
R:
TCCTGTGCTGTTTGCTAAGGC
Band lengths:
250-377
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]