DreEX6081106 @ danRer10
Exon Skipping
Gene
ENSDARG00000011298 | atf7a
Description
activating transcription factor 7a [Source:ZFIN;Acc:ZDB-GENE-050721-2]
Coordinates
chr23:27531623-27534861:-
Coord C1 exon
chr23:27534697-27534861
Coord A exon
chr23:27531968-27532125
Coord C2 exon
chr23:27531623-27531716
Length
158 bp
Sequences
Splice sites
3' ss Seq
TTGGCTGATTATCGTCGCAGGAT
3' ss Score
5.22
5' ss Seq
GGGGTAAGT
5' ss Score
9.65
Exon sequences
Seq C1 exon
TTGCCTGCTCCGAATTCAGGAGCCATAGATATGAGTTTGCAGACGCCTTCAGACGTGAAGGTGAAGGAGGAGGACCCTGTGGAGGTGGACTCCACTCCGCCTACAAGTCCTGACTCCATCTCCAGCATGTCAGACAGCAGCAAAGAACCCGTAGGCAGAGGAAAG
Seq A exon
GATTCTCCTCCAAGGCATGCCTTCAGTTCAGCTCCAACCCCAGCCATAGTGCGTCCTGGATCCCTCCCTCTGCACCTGGGTTATGACGGCCTGCATCCCACCATGCCTTCCCCAACCTCCGTCATCACACACACCCCACCATCCAACCGCACACTGGG
Seq C2 exon
GTCTCCAACAGTGCCATACCCAATGATGATGCTTCCCAATGGTCAAACGGTTCCTGTGCTTCCTGGTCCTATGCAAATGCCCTCTGTAATATCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000011298-'4-7,'4-6,5-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.875
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGCCTGCTCCGAATTCAGGA
R:
GGGCATTTGCATAGGACCAGG
Band lengths:
247-405
Functional annotations
There are 2 annotated functions for this event
PMID: 25301550
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI003062; ELM sequence: RPGSLPL; Overlap: FULL
PMID: 26538579
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: fluorescence polarization spectroscopy, protein array. ELM ID: ELMI003062; ELM sequence: RPGSLPL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]