DreEX6083967 @ danRer10
Exon Skipping
Gene
ENSDARG00000044718 | vav2
Description
vav 2 guanine nucleotide exchange factor [Source:ZFIN;Acc:ZDB-GENE-091204-420]
Coordinates
chr21:17992905-17994867:-
Coord C1 exon
chr21:17994751-17994867
Coord A exon
chr21:17994534-17994621
Coord C2 exon
chr21:17992905-17993028
Length
88 bp
Sequences
Splice sites
3' ss Seq
CATTTCTCTTCTTTTAACAGGTT
3' ss Score
11.4
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
Exon sequences
Seq C1 exon
GTTTGCAGGAAACATGGAGCGGCAGCAGGCCGACAACCTGCTCAAGTCTCACAGCAGCGGCACCTATCTTATCCGAGAGAGAACGGCAGAGGCGGAGAGATTTGCAATCAGCATTAA
Seq A exon
GTTTAATGATGAAGTGAAGCACATTAAAGTTATTGAGAAAGACAACTGGATTCACATCACAGAGGCCAAGAAGTTTGAAAGCCTCTTG
Seq C2 exon
GAGCTTGTGGAGTATTATCAGAGTCATTCACTGAAGGAGAGTTTTAAGCTGTTGGACACAACATTACGGTACCCTTACAAATCCCGGGAACGCTCAAGCTCTCGCACCAATACCCGCTCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000044718-'27-31,'27-30,28-31=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.038 A=0.000 C2=0.238
Domain overlap (PFAM):
C1:
PF0001719=SH2=PU(52.0=97.5)
A:
PF0001719=SH2=FE(38.7=100)
C2:
PF0001719=SH2=PD(6.7=11.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGCTCAAGTCTCACAGCAG
R:
CGTTCCCGGGATTTGTAAGGG
Band lengths:
173-261
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]