DreEX6095966 @ danRer10
Exon Skipping
Gene
ENSDARG00000056888 | DNAH8
Description
dynein, axonemal, heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr24:33745078-33746177:+
Coord C1 exon
chr24:33745078-33745212
Coord A exon
chr24:33745322-33745511
Coord C2 exon
chr24:33745960-33746177
Length
190 bp
Sequences
Splice sites
3' ss Seq
CTATTTTGATCTTCATTCAGGTT
3' ss Score
8.82
5' ss Seq
ACGGTTAGT
5' ss Score
7.37
Exon sequences
Seq C1 exon
GTCCATTATGACTTTGGCTTGAGGAACATCTTGTCTGTTTTAAGAACGTTGGGTGCTGTTAAGAGGTCCAATCCAACAGAGCCAGAAAAGACTGTGGTCATGAGAGTTCTGCGTGACATGAACCTCTCCAAACTG
Seq A exon
GTTGATGAAGATGAGCCTCTGTTCATGAGCCTGATCAATGACCTGTTTCCGGGGATCATGCTGGATAAAGCTGGTTACCCTGACCTGGAAGCTGCTATCACCAAACAAGCTGAAGAAGCAGGACTGATTGCACACCCACCCTGGATTCTTAAACTTGTGCAACTGTATGAGACTCAGAGAGTGAGACACG
Seq C2 exon
GTATGATGACCCTTGGTCCCAGTGGAACAGGAAAAACCACGTGTATCCACACGTTAATGAAAGCCATGACAGACTGTGGAAATCCTCACAAGGAGATGAGGATGAATCCCAAGGCCATCACTGCCTCCCAGATGTTTGGCACATTGGACGTGGCCACAAATGACTGGACAGATGGTATCTTCTCCACACTCTGGCGGAAAACTCTAAAATCCAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000056888-'42-44,'42-43,43-44=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.044 A=0.000 C2=0.178
Domain overlap (PFAM):
C1:
PF127742=AAA_6=PD(10.8=53.3)
A:
PF077289=AAA_5=PU(0.1=0.0)
C2:
PF077289=AAA_5=PU(52.6=98.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGTGCTGTTAAGAGGTCCA
R:
TGTCCAGTCATTTGTGGCCAC
Band lengths:
256-446
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]