DreEX6101257 @ danRer10
Exon Skipping
Gene
ENSDARG00000006921 | lrp5
Description
low density lipoprotein receptor-related protein 5 [Source:ZFIN;Acc:ZDB-GENE-050518-2]
Coordinates
chr25:10611986-10614922:-
Coord C1 exon
chr25:10614791-10614922
Coord A exon
chr25:10612255-10612651
Coord C2 exon
chr25:10611986-10612157
Length
397 bp
Sequences
Splice sites
3' ss Seq
AATCTCTATTTTTTTCCTAGGAG
3' ss Score
8.04
5' ss Seq
TGGGTACGA
5' ss Score
5.84
Exon sequences
Seq C1 exon
TTCAAACTCCATGCAGTGAAAGGAACGGAGGCTGTTCCCACCTGTGTCTTCTCTCCCCCATTCCTCCCTTTTACAGCTGCGCTTGTCCAACAGGGGTTAAGCTCAAAGAGGACGGAAAGACTTGTCGGCCAG
Seq A exon
GAGCAGAACAGGTGCTTTTACTTGCTCGTCGCACTGATCTTCGGCGGATATCCTTGGACTTGCCTGACTTTACAGATATCGTCCTTCAAGTCAATGATATTCGTCATGCAATTGCCATCGATTATGACCCGGTGGAGGGATATGTCTACTGGACGGACGATGAGTTGAGGGCTATACGGCGTGCTCGAATTGATGGAAGCGATGCCCAGACTTTAATCACCAATGAGATCAATCATCCTGATGGAATTGCTGTGGATTGGGTGGCACGAAACCTCTACTGGACGGACACTGGCACAGATCGCATTGAGGTGACCAGACTCAATGGCACTTCTCGACGGGTCCTCATATCTGAGAACCTGGACGAACCACGAGCCATTGTATTGGATCCCATAAATGG
Seq C2 exon
ATACATGTATTGGACTGACTGGGGGGAATTGCCCAAAATTGAACGAGCAAACCTGGATGGCACGGACCGGGTCGTGCTTCTCAACACTTCTCTTGGCTGGCCGAACGGTTTGGCTATAGACTATATAGCCGGAAAGCTTTACTGGGGTGATGCCAAAACAGACAAAATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000006921-'6-10,'6-8,8-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.089 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=84.4)
A:
PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(33.3=22.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCAAACTCCATGCAGTGAAAGGA
R:
CAATTTTGTCTGTTTTGGCATCACC
Band lengths:
302-699
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]